Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
Org Lett. 2011 Dec 2;13(23):6216-9. doi: 10.1021/ol202663p. Epub 2011 Nov 7.
A method has been developed for the intermolecular hydroacylation of homoallyl alcohols with salicylaldehydes to furnish homoaldol products in 50-98% yields. The method also applies to the hydroacylation of 2-hydroxystyrenes. This work highlights the use of hydroacylation as a unified approach to both aldol and homoaldol products.
已经开发出一种方法，用于将偕烯丙基醇与水杨醛进行分子间羟醛缩合，以 50-98%的产率得到同型羟醛缩合产物。该方法也适用于 2-羟基苯乙烯的羟醛缩合。这项工作强调了羟醛缩合作为一种统一的方法，可用于制备羟醛缩合产物和同型羟醛缩合产物。
