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衰老的理论和机制。

Theories and mechanisms of aging.

机构信息

Department of Medicine, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA 70113, USA.

出版信息

Clin Geriatr Med. 2011 Nov;27(4):491-506. doi: 10.1016/j.cger.2011.07.001. Epub 2011 Sep 22.

DOI:10.1016/j.cger.2011.07.001
PMID:22062437
Abstract

This article discusses various theories of aging and their relative plausibility related to the human aging process. Structural and physiologic changes of aging are discussed in detail by organ system. Each of the organ systems is discussed when applicable to the various theories of aging. Normal versus abnormal aging is discussed in the context of specific aging processes, with atypical presentations of disease and general links to life expectancy. Life expectancy and lifespan are discussed in the context of advances in medical science and the potential ultimate link to human life span.

摘要

本文讨论了与人类衰老过程相关的各种衰老理论及其相对合理性。按器官系统详细讨论了衰老的结构和生理变化。在讨论各种衰老理论时,适当地讨论了每个器官系统。在特定的衰老过程中,讨论了正常衰老与异常衰老,以及疾病的非典型表现与预期寿命的一般联系。在医学科学进步的背景下讨论了预期寿命和寿命,以及与人类寿命的潜在最终联系。

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