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尼日利亚卡诺市穆尔塔拉·穆罕默德专科医院子痫患者的母婴结局

Maternal and fetal outcome in patients with eclampsia at Murtala Muhammad specialist Hospital Kano, Nigeria.

作者信息

Yakasai Ibrahim A, Gaya Sule A

机构信息

Department of Obstetrics and Gynaecology, Aminu Kano Teaching Hospital Kano, Nigeria.

出版信息

Ann Afr Med. 2011 Oct-Dec;10(4):305-9. doi: 10.4103/1596-3519.87049.

Abstract

BACKGROUND/OBJECTIVES: Eclampsia is a major contributor to maternal and perinatal mortality worldwide. It is much more common in developing countries like Nigeria where presentation is usually late and resources are scarce. The staggering figures of maternal death (46%) reported by the Society of Obstetricians and Gynaecologists of Nigeria (SOGON) in 2004 moved the Kano State government to initiate programs that will reduce maternal mortality in the state. The objectives of this report were; 1) to determine the prevalence of eclampsia at Murtala Muhammad Specialist hospital (MMSH) Kano between April 2008 and May 2009; 2) to determine maternal and fetal outcome in eclamptic patients admitted to MMSH Kano between April 2008 and May 2009.

METHODS

Case records of all patients admitted to MMSH between April 2008 and May 2009 were retrieved and analyzed using Epi-info version 3.2.2 April 2004 (CDC Atlanta, USA). Information extracted includes demographic data, maternal and fetal outcome. A P value of less than 0.05 was considered significant.

RESULTS

There were 688 eclamptic patients admitted and 13 943 women delivered during the study period giving a prevalence of 5% of total deliveries. One hundred and twenty six women died giving a maternal mortality ratio (MMR) of 904/100 000, among them 36 were eclamptics. The perinatal mortality rate for the eclamptics was 132/1 000. 81.4% of the women were primigravidas and majority (82.2%) were at term. Almost 83.3% presented within 12 hours of the onset of the fits and nearly half (44.9%) had their convulsion before the onset of labor.

CONCLUSION

The incidence of eclampsia is 5% of total deliveries. Delay in presentation is associated with poor outcome.

摘要

背景/目的:子痫是全球孕产妇和围产儿死亡的主要原因之一。在尼日利亚等发展中国家更为常见,这些国家通常就诊较晚且资源匮乏。2004年尼日利亚妇产科学会(SOGON)报告的惊人孕产妇死亡率(46%)促使卡诺州政府启动了旨在降低该州孕产妇死亡率的项目。本报告的目的是:1)确定2008年4月至2009年5月期间卡诺穆尔塔拉·穆罕默德专科医院(MMSH)的子痫患病率;2)确定2008年4月至2009年5月期间入住卡诺MMSH的子痫患者的母婴结局。

方法

检索并使用美国疾病控制与预防中心(CDC,亚特兰大)2004年4月版Epi-info 3.2.2对2008年4月至2009年5月期间入住MMSH的所有患者的病历进行分析。提取的信息包括人口统计学数据、母婴结局。P值小于0.05被认为具有统计学意义。

结果

在研究期间,有688例子痫患者入院,13943名妇女分娩,子痫患病率占总分娩数的5%。126名妇女死亡,孕产妇死亡率(MMR)为904/100000,其中36例为子痫患者。子痫患者的围产儿死亡率为132/1000。81.4%的妇女为初产妇,大多数(82.2%)为足月产。近83.3%的患者在抽搐发作后12小时内就诊,近一半(44.9%)在分娩发动前发生惊厥。

结论

子痫发病率占总分娩数的5%。就诊延迟与不良结局相关。

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