结节病性突发性聋：听神经病学研究及神经放射学相关表现。
Sudden hearing loss in sarcoidosis: otoneurological study and neuroradiological correlates.
机构信息
Audiology and Phoniatrics Service, Department of Medical and Surgical Specialities, University of Padua, Padova.
出版信息
Acta Otorhinolaryngol Ital. 2011 Aug;31(4):235-8.
Abstract
Sarcoidosis is an inflammatory multisystem disorder of unknown cause. Approximately 5-7% of patients manifest symptoms of central nervous system involvement, or neurosarcoidosis. Cranial neuropathy usually entails facial nerve palsy and optic neuritis. Sudden hearing loss has been reported in fewer than 20 cases. Herewith, two new cases of sudden hearing loss due to probable neurosarcoidosis are reported, each having a quite different clinical course. In one case, unilateral sudden hearing loss and facial palsy were the presenting symptoms of systemic sarcoidosis, while in the second, unilateral sudden deafness occurred despite ongoing immunosuppressive treatment for systemic sarcoidosis.
摘要
结节病是一种原因不明的炎症性多系统疾病。约 5-7%的患者表现出中枢神经系统受累的症状，即神经结节病。颅神经病变通常包括面神经瘫痪和视神经炎。据报道，突发性听力损失少于 20 例。本文报道了两例可能由神经结节病引起的突发性听力损失新病例，每个病例的临床过程都截然不同。在一个病例中，单侧突发性听力损失和面瘫是系统性结节病的首发症状，而在第二个病例中，尽管正在进行系统性结节病的免疫抑制治疗，但仍出现单侧突发性耳聋。
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