Gott P S, Kumar V, Kadakia J, Sharma O P
Department of Neurology, University of Southern California School of Medicine, Los Angeles 90033, USA.
Sarcoidosis Vasc Diffuse Lung Dis. 1997 Sep;14(2):159-64.
To assess central nervous system (CNS) involvement with normal CNS examination, multimodality evoked potentials were obtained in 25 patients with confirmed multisystem sarcoidosis. Twelve patients had abnormal evoked potentials: brainstem auditory evoked potentials (BAEP) were abnormal in 5, median nerve somatosensory evoked potentials (SEP) were abnormal in 4, and visual evoked potentials (VEP) were abnormal in 6 patients. Contrast-enhanced magnetic resonance imaging (MRI) of the brain in two patients with abnormal evoked potentials revealed no supportive structural lesions. Multimodality evoked potentials can detect subclinical neurosarcoidosis and are an important adjunct to neuroradiology in the diagnosis of neurosarcoidosis.
为评估中枢神经系统(CNS)受累情况,尽管中枢神经系统检查正常,我们对25例确诊为多系统结节病的患者进行了多模态诱发电位检查。12例患者诱发电位异常:5例脑干听觉诱发电位(BAEP)异常,4例正中神经体感诱发电位(SEP)异常,6例视觉诱发电位(VEP)异常。2例诱发电位异常患者的脑部对比增强磁共振成像(MRI)未发现支持性结构病变。多模态诱发电位可检测亚临床神经结节病,是神经结节病诊断中神经放射学的重要辅助手段。