Rocco Francesco, Cozzi Gabriele, Spinelli Matteo Giulio, Rocco Bernardo Maria, Albo Giancarlo, Finkelberg Elisabetta, Oliva Isabella, Fontanella Paolo, Varisco Daniela, Moneghini Laura, Talso Michele, Palumbo Carlotta
Department of Urology , Università degli Studi di Milano, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan;
Rare Tumors. 2011 Jul 11;3(3):e31. doi: 10.4081/rt.2011.e31. Epub 2011 Jul 20.
Aggressive angiomyxoma (AAM) is a rare mesenchymal benign myxoid tumor, characterized by locally infiltrative nature and high recurrence rate. AAM occurs almost exclusively in adult females, arising from the soft tissue of the pelvic region: to our knowledge, only 43 cases occurring in men have been reported. We report a case of massive recurrence of scrotal AAM in a 46-year-old obese man, who already underwent surgery for the same disease in 2004 and 2005. The mass had a circumference of 106 cm and weighted 30 kg. It was impossible to appreciate the testes and to find the penis. The patient underwent scrotal resection, bilateral orchidopexia and transposition of the penis, by means of a preputial flap. Residual scrotal skin was modeled in order to create a neoscrotum, where the testes were placed and secured with interrupted sutures. Histologic examination showed diffuse angiomyxoma-like lipomatosis. After three months, the patient presented with local relapse which also involved the external urethral orifice.
侵袭性血管黏液瘤（AAM）是一种罕见的间叶性良性黏液样肿瘤，具有局部浸润性和高复发率的特点。AAM几乎仅发生于成年女性，起源于盆腔区域的软组织：据我们所知，仅有43例发生于男性的病例报道。我们报告一例46岁肥胖男性阴囊AAM大量复发的病例，该患者曾在2004年和2005年因同一疾病接受过手术。肿块周长为106 cm，重达30 kg。无法触及睾丸，也找不到阴茎。患者接受了阴囊切除术、双侧睾丸固定术及阴茎转位术，采用包皮瓣进行。对残留的阴囊皮肤进行塑形以形成新阴囊，将睾丸置于其中并用间断缝线固定。组织学检查显示弥漫性血管黏液瘤样脂肪瘤病。三个月后，患者出现局部复发，累及外尿道口。
