Nilsson S, Berglund I, Christoffersson A, Erikson U, Högman N, Johansson J, Lörelius L E, Roberts R G, Walldius G
Department of Diagnostic Radiology, University of Uppsala, Sweden.
Acta Radiol. 1990 Jul;31(4):333-9.
Regular, wave-like constriction in medium-sized arteries, arterial segmental vasoconstriction (ASV), has been observed at arteriography and described by many authors. We found ASV in arteriograms of the superficial femoral artery in 13 of 107 hypercholesterolaemic patients, enrolled in the Probucol Quantitative Regression Swedish Trial (PQRST). The arteriograms were digitized and studied with a quantitative computer-assisted technique. The frequency of ASV was higher than has been reported earlier in clinical materials, possibly because of an increased vasoreactivity in hypercholesterolaemia, as recently observed experimentally. The ASV patients were, on average, younger, had lower blood pressure and less atherosclerosis, than the non-ASV patients. ASV was not found in any of the 19 patients in the material who either had symptoms of peripheral vascular disease or arteriographically verified arterial occlusions. No significant correlations with smoking habits or serum cholesterol levels were found. A computer-based index of ASV and measurement of ASV wavelength are discussed.
在动脉造影中观察到中等大小动脉出现规律的、波浪状收缩，即动脉节段性血管收缩（ASV），许多作者对此进行了描述。在参与普罗布考定量回归瑞典试验（PQRST）的107例高胆固醇血症患者中，我们在13例患者的股浅动脉血管造影中发现了ASV。血管造影数字化后采用定量计算机辅助技术进行研究。ASV的发生率高于此前临床资料中的报道，这可能是由于高胆固醇血症中血管反应性增加，正如最近实验观察到的那样。与非ASV患者相比，ASV患者平均年龄更小，血压更低，动脉粥样硬化程度更轻。在该研究材料中，19例有外周血管疾病症状或经动脉造影证实有动脉闭塞的患者中均未发现ASV。未发现与吸烟习惯或血清胆固醇水平有显著相关性。本文讨论了基于计算机的ASV指数和ASV波长测量方法。
