Nilsson S, Berglund I, Erikson U, Högman N, Johansson J, Walldius G
Department of Diagnostic Radiology, Akademiska Sjukhuset, University of Uppsala, Sweden.
Acta Radiol. 1991 Jan;32(1):24-9.
Atherosclerosis is reflected in the arteriogram as narrowing of the arterial lumen and irregularity of the arterial wall. We have quantified these changes in digitized femoral arteriograms from 107 hypercholesterolaemic patients and defined 10 different measures concerning arterial diameter, cross-sectional area, stenosis and edge irregularity. We examined the precision of these measures and the correlations between them. Lumen volume and mean diameter for defined arterial segments had the highest precision and may be useful for follow-up studies. The linear correlation between the mean diameter and the square root of the lumen volume was greater than 0.99, so these two measures seem to be equivalent for all practical purposes. The measured variables could be separated into 2 groups: the measures concerning arterial diameter and lumen volume and those concerning edge irregularity and localized stenosis. The measures within each group showed strong positive mutual correlations, while the correlations between measures from different groups were negative and small. It was concluded that if the results of one measure from each group, suitably those of lumen volume and edge roughness, are known, the other described measures will add no further information about the atherosclerotic process.
动脉粥样硬化在动脉造影片上表现为动脉管腔狭窄和动脉壁不规则。我们对107例高胆固醇血症患者的数字化股动脉造影片上的这些变化进行了量化，并定义了10种关于动脉直径、横截面积、狭窄和边缘不规则的不同测量方法。我们研究了这些测量方法的精度以及它们之间的相关性。特定动脉节段的管腔容积和平均直径具有最高的精度，可能对随访研究有用。平均直径与管腔容积平方根之间的线性相关性大于0.99，因此这两种测量方法在所有实际应用中似乎是等效的。所测量的变量可分为两组：关于动脉直径和管腔容积的测量方法以及关于边缘不规则和局部狭窄的测量方法。每组内的测量方法显示出强烈的正相互相关性，而不同组测量方法之间的相关性为负且较小。得出的结论是，如果知道每组中一种测量方法的结果，合适的是管腔容积和边缘粗糙度的结果，那么其他所描述的测量方法将不会提供关于动脉粥样硬化过程的更多信息。
