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本文引用的文献

1
PaCO2 and alveolar dead space are more relevant than PaO2/FiO2 ratio in monitoring the respiratory response to prone position in ARDS patients: a physiological study.动脉血二氧化碳分压和肺泡死腔量比 PaO2/FiO2 比值更能反映 ARDS 患者俯卧位通气时的呼吸反应：一项生理学研究。
Crit Care. 2011 Jul 25;15(4):R175. doi: 10.1186/cc10324.
2
Assessing gas exchange in acute lung injury/acute respiratory distress syndrome: diagnostic techniques and prognostic relevance.评估急性肺损伤/急性呼吸窘迫综合征中的气体交换：诊断技术和预后相关性。
Curr Opin Crit Care. 2011 Feb;17(1):18-23. doi: 10.1097/MCC.0b013e32834272d8.
3
Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials.床边使用常规临床数据对急性肺损伤患者死腔分数进行定量分析：两项前瞻性试验的二次分析。
Crit Care. 2010;14(4):R141. doi: 10.1186/cc9206. Epub 2010 Jul 29.
4
Therapeutic strategies for severe acute lung injury.严重急性肺损伤的治疗策略。
Crit Care Med. 2010 Aug;38(8):1644-50. doi: 10.1097/CCM.0b013e3181e795ee.
5
Prognostic value of the pulmonary dead-space fraction during the early and intermediate phases of acute respiratory distress syndrome.急性呼吸窘迫综合征早期和中期肺死腔分数的预后价值。
Respir Care. 2010 Mar;55(3):282-7.
6
Randomized clinical trial of activated protein C for the treatment of acute lung injury.活化蛋白C治疗急性肺损伤的随机临床试验。
Am J Respir Crit Care Med. 2008 Sep 15;178(6):618-23. doi: 10.1164/rccm.200803-419OC. Epub 2008 Jun 19.
7
Pulmonary dead space fraction and pulmonary artery systolic pressure as early predictors of clinical outcome in acute lung injury.肺死腔分数和肺动脉收缩压作为急性肺损伤临床结局的早期预测指标。
Chest. 2007 Sep;132(3):836-42. doi: 10.1378/chest.07-0409. Epub 2007 Jun 15.
8
Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome.急性呼吸窘迫综合征最初6天内肺死腔分数的预后价值
Respir Care. 2004 Sep;49(9):1008-14.
9
Respiratory system mechanics in acute respiratory distress syndrome.急性呼吸窘迫综合征中的呼吸系统力学
Respir Care Clin N Am. 2003 Sep;9(3):297-319. doi: 10.1016/s1078-5337(03)00040-6.
10
Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndrome.急性呼吸窘迫综合征患者俯卧位时动脉血二氧化碳分压（PaCO2）降低预示着预后改善。
Crit Care Med. 2003 Dec;31(12):2727-33. doi: 10.1097/01.CCM.0000098032.34052.F9.

急性呼吸窘迫综合征患者肺死腔的预后价值。

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome.

机构信息

Department of Medicine and Cardiovascular Research Institute at University of California, San Francisco, 505 Parnassus Avenue, M-917, San Francisco, CA 94143-0624, USA.

出版信息

Crit Care. 2011;15(5):185. doi: 10.1186/cc10346. Epub 2011 Oct 25.

DOI:10.1186/cc10346
PMID:22067424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3334730/
Abstract

A study published in the previous issue of Critical Care demonstrates that measurement of the pulmonary dead-space fraction is superior to hypoxemia as an indicator of a favorable physiologic response to prone positioning in patients with severe acute respiratory distress syndrome. These results add to the growing evidence supporting the clinical and research value of measuring pulmonary dead space in patients with acute respiratory distress syndrome and using this pulmonary physiologic end-point as one indicator of a favorable response to therapy.

摘要

上一期《危重病医学》发表的一项研究表明，与低氧血症相比，测量死腔分数可更好地预测严重急性呼吸窘迫综合征患者俯卧位通气的生理反应良好。这些结果进一步证明了测量急性呼吸窘迫综合征患者死腔的临床和研究价值，并将该肺生理终点作为治疗反应良好的指标之一。