• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The human plasma lipidome.

作者信息

Quehenberger Oswald, Dennis Edward A

机构信息

Departments of Medicine and Pharmacology, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0601, USA.

出版信息

N Engl J Med. 2011 Nov 10;365(19):1812-23. doi: 10.1056/NEJMra1104901.

DOI:10.1056/NEJMra1104901
PMID:22070478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3412394/
Abstract
摘要

相似文献

1
The human plasma lipidome.人类血浆脂质组。
N Engl J Med. 2011 Nov 10;365(19):1812-23. doi: 10.1056/NEJMra1104901.
2
The human plasma lipidome.人类血浆脂质组
N Engl J Med. 2012 Feb 16;366(7):668; author reply 668-9. doi: 10.1056/NEJMc1114201.
3
Markers of sympathetic nervous system activity associate with complex plasma lipids in metabolic syndrome subjects.在代谢综合征患者中，交感神经系统活动标志物与复杂血浆脂质相关。
Atherosclerosis. 2017 Jan;256:21-28. doi: 10.1016/j.atherosclerosis.2016.11.032. Epub 2016 Dec 1.
4
Weight Loss and Exercise Alter the High-Density Lipoprotein Lipidome and Improve High-Density Lipoprotein Functionality in Metabolic Syndrome.体重减轻和运动改变代谢综合征患者高密度脂蛋白脂质组并改善高密度脂蛋白功能。
Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):438-447. doi: 10.1161/ATVBAHA.117.310212. Epub 2017 Dec 28.
5
[Serum lipids and lipid absorption studies on mixed patients of a neurological hospital].[一家神经科医院混合患者的血脂及脂质吸收研究]
Acta Psychiatr Scand. 1969;45(1):90-103. doi: 10.1111/j.1600-0447.1969.tb06204.x.
6
Alterations of specific lipid groups in serum of obese humans: a review.肥胖人群血清中特定脂质组的改变：综述。
Obes Rev. 2017 Feb;18(2):247-272. doi: 10.1111/obr.12475. Epub 2016 Nov 29.
7
Major plasma lipids and their fatty acid composition in multiple sclerosis and other neurological diseases.多发性硬化症及其他神经疾病中的主要血浆脂质及其脂肪酸组成
Acta Neurol Scand. 1971;47(4):403-12. doi: 10.1111/j.1600-0404.1971.tb07495.x.
8
Blood plasma lipidomic signature of epicardial fat in healthy obese women.健康肥胖女性心外膜脂肪的血浆脂质组学特征
Obesity (Silver Spring). 2015 Jan;23(1):130-7. doi: 10.1002/oby.20925. Epub 2014 Nov 15.
9
Serum lipidomics reveals early differential effects of gastric bypass compared with banding on phospholipids and sphingolipids independent of differences in weight loss.血清脂质组学揭示了与束带术相比，胃旁路手术对磷脂和鞘脂的早期差异影响，且这种影响独立于体重减轻的差异。
Int J Obes (Lond). 2017 Jun;41(6):917-925. doi: 10.1038/ijo.2017.63. Epub 2017 Mar 10.
10
Integrative Analysis of Lipid Profiles in Plasma Allows Cardiometabolic Risk Factor Clustering in Children with Metabolically Unhealthy Obesity.血浆脂质谱的综合分析可使代谢不健康肥胖儿童的心血管代谢风险因素聚类。
Oxid Med Cell Longev. 2020 Aug 11;2020:2935278. doi: 10.1155/2020/2935278. eCollection 2020.

引用本文的文献

1
Site-Specific Trafficking of Lipid and Polar Metabolites in Adipose and Muscle Tissue Reveals the Impact of Bariatric Surgery-Induced Weight Loss: A 6-Month Follow-Up Study.脂肪和肌肉组织中脂质及极性代谢物的位点特异性转运揭示了减肥手术所致体重减轻的影响：一项为期6个月的随访研究
Metabolites. 2025 Aug 2;15(8):525. doi: 10.3390/metabo15080525.
2
Obtaining and Characterization of Nutraceuticals Based on Linoleic Acid Derivatives Obtained by Green Synthesis and Their Valorization in the Food Industry.基于绿色合成获得的亚油酸衍生物的营养保健品的制备、表征及其在食品工业中的价值提升
Nutrients. 2025 Jul 24;17(15):2416. doi: 10.3390/nu17152416.
3
Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis.糖胺聚糖驱动的脂蛋白摄取可保护肿瘤免受铁死亡。
Nature. 2025 Jun 11. doi: 10.1038/s41586-025-09162-0.
4
Human gut commensal modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an -deficient mouse model.人类肠道共生菌调节宿主脂质组，并递送抗炎性外膜囊泡以抑制β-缺陷小鼠模型中的结肠炎。
Gut Microbes. 2025 Dec;17(1):2517380. doi: 10.1080/19490976.2025.2517380. Epub 2025 Jun 11.
5
Interactive Effect of Plasma Lipidome on Neuropsychiatric Disorders: A Bidirectional Mendelian Randomization Study.血浆脂质组对神经精神疾病的交互作用：一项双向孟德尔随机化研究
Mol Neurobiol. 2025 Jun 3. doi: 10.1007/s12035-025-05105-y.
6
Ceramides in cardiovascular disease: emerging role as independent risk predictors and novel therapeutic targets.心血管疾病中的神经酰胺：作为独立风险预测因子和新型治疗靶点的新作用。
Cardiovasc Res. 2025 Aug 14;121(9):1345-1358. doi: 10.1093/cvr/cvaf093.
7
Accurate Determination of Circulatory Lipids Using a Combination of HILIC-MRM and RPLC-PRM.使用亲水作用色谱-多反应监测（HILIC-MRM）和反相液相色谱-多反应监测（RPLC-PRM）联用技术准确测定循环脂质
Anal Chem. 2025 May 13;97(18):9713-9721. doi: 10.1021/acs.analchem.4c06409. Epub 2025 May 2.
8
Exploring the protective role of maternal lung cancer history on allergic rhinitis.探讨母亲肺癌病史对过敏性鼻炎的保护作用。
J Clin Biochem Nutr. 2025 Mar;76(2):156-163. doi: 10.3164/jcbn.24-172. Epub 2024 Dec 27.
9
Exploring Oxylipins in Host-Microbe Interactions and Their Impact on Infection and Immunity.探索氧化脂质在宿主-微生物相互作用中的作用及其对感染和免疫的影响。
Curr Issues Mol Biol. 2025 Mar 14;47(3):190. doi: 10.3390/cimb47030190.
10
Clinical lipidomics reveals high individuality and sex specificity of circulatory lipid signatures: a prospective healthy population study.临床脂质组学揭示循环脂质特征的高度个体性和性别特异性：一项前瞻性健康人群研究。
J Lipid Res. 2025 Mar 18;66(5):100780. doi: 10.1016/j.jlr.2025.100780.

本文引用的文献

1
Applications of mass spectrometry to lipids and membranes.质谱在脂质和膜中的应用。
Annu Rev Biochem. 2011;80:301-25. doi: 10.1146/annurev-biochem-060409-092612.
2
Metabolome in schizophrenia and other psychotic disorders: a general population-based study.精神分裂症和其他精神病性障碍中的代谢组学：一项基于一般人群的研究。
Genome Med. 2011 Mar 23;3(3):19. doi: 10.1186/gm233.
3
Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy.血清脂质组学与心脏磁共振成像：扩张型心肌病风险患者的特征分析。
PLoS One. 2011 Jan 20;6(1):e15744. doi: 10.1371/journal.pone.0015744.
4
Comparison of total plasma lysophosphatidic acid and serum CA-125 as a tumor marker in the diagnosis and follow-up of patients with epithelial ovarian cancer.比较总血浆溶血磷脂酸和血清 CA-125 作为上皮性卵巢癌诊断和随访的肿瘤标志物。
J Gynecol Oncol. 2010 Dec 30;21(4):248-54. doi: 10.3802/jgo.2010.21.4.248. Epub 2010 Dec 31.
5
Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study.反式棕榈油酸、代谢风险因素与美国成年人新发糖尿病：一项队列研究。
Ann Intern Med. 2010 Dec 21;153(12):790-9. doi: 10.7326/0003-4819-153-12-201012210-00005.
6
Sphingolipid profiling of human plasma and FPLC-separated lipoprotein fractions by hydrophilic interaction chromatography tandem mass spectrometry.采用亲水相互作用色谱串联质谱法对人血浆及快速蛋白质液相色谱分离的脂蛋白组分进行鞘脂分析。
Biochim Biophys Acta. 2011 Feb;1811(2):68-75. doi: 10.1016/j.bbalip.2010.11.003. Epub 2010 Nov 23.
7
Lysophosphatidic acid (LPA)—a perspective marker in ovarian cancer.溶血磷脂酸（LPA）——卵巢癌的一种潜在标志物。
Tumour Biol. 2011 Apr;32(2):311-6. doi: 10.1007/s13277-010-0123-8.
8
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.芬戈莫德（FTY720）：一种治疗多发性硬化症的口服药物的发现和开发。
Nat Rev Drug Discov. 2010 Nov;9(11):883-97. doi: 10.1038/nrd3248. Epub 2010 Oct 29.
9
Circulating palmitoleic acid and risk of metabolic abnormalities and new-onset diabetes.循环棕榈油酸与代谢异常和新发糖尿病的风险。
Am J Clin Nutr. 2010 Dec;92(6):1350-8. doi: 10.3945/ajcn.110.003970. Epub 2010 Oct 13.
10
A mouse macrophage lipidome.鼠源巨噬细胞脂类组
J Biol Chem. 2010 Dec 17;285(51):39976-85. doi: 10.1074/jbc.M110.182915. Epub 2010 Oct 5.