Yonge Eglinton Laser Eye Center, University Health Network, Toronto, Ontario, Canada.
J Refract Surg. 2011 Dec;27(12):915-8. doi: 10.3928/1081597X-20111103-03. Epub 2011 Nov 10.
To evaluate the efficacy of intrastromal corneal ring segments implantation followed by same-day photorefractive keratectomy (PRK) and ultraviolet-A/riboflavin collagen cross-linking (CXL) in patients with keratoconus.
Four patients (five eyes) were included in the study. All patients first underwent femtosecond laser-enabled placement of intracorneal ring segments (Intacs, Addition Technology). Uncorrected (UDVA) and corrected distance visual acuity (CDVA) and keratometry readings remained stable for 6 months. Same-day PRK and CXL were subsequently performed in all patients.
Six months after Intacs plus PRK/CXL, significant improvements were noted for UDVA, CDVA, spherical equivalent refraction, keratometry, and total aberrations. No patient lost lines of CDVA or developed haze.
The combination of intracorneal ring segments implantation followed by sequential same-day PRK/CXL may be a reasonable option for improving visual acuity in select patients with keratoconus.
评估角膜基质环段植入联合当日光性折射性角膜切削术（PRK）和紫外线 A/核黄素胶原交联（CXL）治疗圆锥角膜的疗效。
本研究纳入了 4 名患者（5 只眼）。所有患者均首先接受飞秒激光辅助的角膜内环段植入（Intacs，Addition Technology）。未矫正（UDVA）和矫正距离视力（CDVA）以及角膜曲率读数在 6 个月内保持稳定。所有患者随后均接受当日 PRK 和 CXL。
Intacs 联合 PRK/CXL 治疗 6 个月后，UDVA、CDVA、等效球镜屈光度、角膜曲率和总像差均显著改善。无一例患者丧失 CDVA 或出现混浊。
角膜基质环段植入联合序贯当日 PRK/CXL 可能是改善特定圆锥角膜患者视力的合理选择。
