Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Clin Nutr. 2012 Apr;31(2):267-72. doi: 10.1016/j.clnu.2011.10.011. Epub 2011 Nov 8.
BACKGROUND & AIMS: Results of previous studies on tea consumption and incidence or prognosis of acute myocardial infarction (AMI) are conflicting. The aim of the present study was to examine the potential role of tea consumption in the previous 12 months in primary and secondary prevention of AMI.
We studied a total of 1340 individuals with a first non-fatal AMI and 2303 frequency matched control participants on age, gender and hospital catchment area including querying their tea consumption over the previous 12 months. The cohort of AMI cases was then followed for total and cardiac mortality and for non-fatal cardiovascular events with national registers over 8 years. Estimates of relative risks for a first AMI were based on odds ratios from unconditional logistic regression and Cox proportional hazards models were used to examine the prognostic importance of tea consumption in the cohort of cases.
The prevalence of daily tea consumption was 20.5% among cases and 21.5% among controls. Tea consumption was associated with a lower risk for a first AMI with adjustment for matching criteria alone, with an odds ratio of 0.78 (95% confidence interval, 0.64-0.95) comparing those who consumed tea daily to those never consuming tea. However, in multivariable adjusted model there was no evidence for an association, the corresponding odds ratio was 1.08(0.86-1.36). There was also no association between tea consumption and cardiac mortality and non-fatal cardiovascular events, with a corresponding adjusted hazard ratio of 0.99(0.77-1.27).
In this epidemiological study, greater tea consumption in the previous year was associated with a lower risk of AMI. However, a clear association between tea consumption and the incidence or prognosis of AMI was not demonstrated, probably because of tea drinkers having a healthier lifestyle.
先前关于饮茶与急性心肌梗死（AMI）发生率或预后关系的研究结果存在争议。本研究旨在探讨过去 12 个月内饮茶在 AMI 一级和二级预防中的潜在作用。
我们共研究了 1340 例首次非致死性 AMI 患者和 2303 例年龄、性别和医院分布相匹配的对照组患者，询问了他们过去 12 个月的饮茶情况。随后，通过国家登记系统对 AMI 病例队列进行了 8 年的全因和心脏死亡率以及非致死性心血管事件随访。首次 AMI 的相对风险估计值基于非条件逻辑回归的比值比，并使用 Cox 比例风险模型来检验病例队列中饮茶对预后的重要性。
病例组中每日饮茶的患病率为 20.5%，对照组中为 21.5%。单独调整匹配标准后，与从不饮茶者相比，每日饮茶者发生首次 AMI 的风险较低，比值比为 0.78（95%置信区间，0.64-0.95）。然而，在多变量调整模型中，没有证据表明两者之间存在关联，相应的比值比为 1.08（0.86-1.36）。饮茶与心脏死亡率和非致死性心血管事件之间也没有关联，相应的调整后危险比为 0.99（0.77-1.27）。
在这项流行病学研究中，过去一年中更多的饮茶与 AMI 风险降低相关。然而，并没有明确的证据表明饮茶与 AMI 的发生或预后之间存在关联，这可能是因为饮茶者的生活方式更为健康。
