Laboratoire de Parasitologie-Mycologie, Centre Hospitalier et Universitaire de Rennes, Rennes, France.
Trends Parasitol. 2011 Dec;27(12):530-6. doi: 10.1016/j.pt.2011.09.005. Epub 2011 Nov 11.
Systemic infections, such as toxoplasmosis, acquired during pregnancy can lead to placental infection and have profound effects on the mother-to-child relationship and the success of pregnancy. Placental permeability to Toxoplasma gondii is a main parameter that determines parasite transmission to the foetus, and the use of antibiotics to decrease placental parasite load and prevent congenital toxoplasmosis has been suggested for decades. Although parasitological examination of the placenta at birth is commonly used to diagnose neonatal congenital toxoplasmosis, this approach can be controversial. Here we argue in favour of placental examination for both diagnostic and epidemiological purposes.
系统性感染，如妊娠期感染弓形体病，可导致胎盘感染，并对母婴关系和妊娠结局产生深远影响。胎盘对弓形虫的通透性是决定寄生虫向胎儿传播的主要参数，几十年来，人们一直建议使用抗生素来降低胎盘寄生虫载量，预防先天性弓形虫病。尽管出生时胎盘寄生虫学检查常用于诊断新生儿先天性弓形虫病，但这种方法可能存在争议。在这里，我们赞成出于诊断和流行病学目的而进行胎盘检查。
