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围产期对山羊(Capra hircus)血清脂质和胆固醇脂蛋白浓度的影响。

Effect of the periparturient period on serum lipid and cholesterol lipoprotein concentrations in goats (Capra hircus).

作者信息

Skotnicka Ewa, Muszczyński Zbigniew, Suska Maria

机构信息

University of Szczecin Department of Physiology, Institute of Life Sciences ul. Felczaka 3a 71-412 Szczecin Poland.

出版信息

Acta Vet Hung. 2011 Dec;59(4):445-54. doi: 10.1556/AVet.2011.032.

DOI:10.1556/AVet.2011.032
PMID:22079706
Abstract

Blood samples were taken from 12 goats during the periparturient period (4 and 1 weeks before and 2, 10 and 30 days after delivery), and from 10 nonpregnant goats. The following variables were determined: total lipids (TL), triacylglycerol (TG), total cholesterol (TCH) and high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol fractions. One week before delivery TL (2.32 ± 0.12 g/l, P ≤ 0.05), TG (0.32 ± 0.16 mmol/l, P ≤ 0.001) and TCH concentrations (1.65 ± 0.42 mmol/l, P ≤ 0.05) were significantly increased as compared to non-pregnant goats (2.08 ± 0.28 g/l, 0.15 ± 0.05 mmol/l, 1.38 ± 0.19 mmol/l, respectively). After delivery, the concentrations of TL, TG, TCH and HDL decreased significantly. The lowest TG concentration was observed 2 days after delivery (0.18 ± 0.02 mmol/l), while TL (1.73 ± 0.21 g/l), TCH (0.95 ± 0.21 mmol/l) and HDL (0.74 ± 0.16 mmol/l) reached the lowest level 10 days after delivery. Two days after delivery a significant increase of LDL concentration was observed (0.38 ± 0.04 mmol/l); however, ten days after delivery a threefold decrease was shown in the LDL concentration (0.12 ± 0.04 mmol/l). A month after delivery all the variables studied reached levels similar to those measured in non-pregnant goats.

摘要

在围产期(分娩前4周和1周以及分娩后2天、10天和30天)从12只山羊采集血样,并从10只未怀孕的山羊采集血样。测定了以下变量:总脂质(TL)、三酰甘油(TG)、总胆固醇(TCH)以及高密度脂蛋白(HDL)胆固醇和低密度脂蛋白(LDL)胆固醇组分。与未怀孕山羊(分别为2.08±0.28g/l、0.15±0.05mmol/l、1.38±0.19mmol/l)相比,分娩前1周TL(2.32±0.12g/l,P≤0.05)、TG(0.32±0.16mmol/l,P≤0.001)和TCH浓度(1.65±0.42mmol/l,P≤0.05)显著升高。分娩后,TL、TG、TCH和HDL浓度显著下降。TG浓度在分娩后2天最低(0.18±0.02mmol/l),而TL(1.73±0.21g/l)、TCH(0.95±0.21mmol/l)和HDL(0.74±0.16mmol/l)在分娩后10天达到最低水平。分娩后2天观察到LDL浓度显著升高(0.38±0.04mmol/l);然而,分娩后10天LDL浓度下降了三倍(0.12±0.04mmol/l)。分娩后一个月,所有研究变量达到与未怀孕山羊测量值相似的水平。

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