Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA.
Rev Cardiovasc Med. 2011;12(3):164-7.
Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning or reversible midventricular systolic dysfunction. Most cases occur in postmenopausal women and are typically triggered by an acute medical illness or emotional or physical stress. Its presentation is highly suggestive of myocardial ischemia, but there is little or no evidence of epicardial coronary artery disease. To our knowledge there are only three reported cases in the literature of Takotsubo cardiomyopathy induced by opioid agonist withdrawal in adults; ours is the first reported case of iatrogenic methadone withdrawal leading to Takotsubo cardiomyopathy.
应激性心肌病是一种综合征，其特征为短暂的心尖球囊样变或可逆性的中部心室收缩功能障碍。大多数病例发生于绝经后女性，通常由急性疾病或情绪或身体应激引发。其临床表现高度提示心肌缺血，但很少或没有心外膜冠状动脉疾病的证据。据我们所知，文献中仅有三例成人阿片类激动剂戒断引起应激性心肌病的报道；我们报告的首例医源性美沙酮戒断导致应激性心肌病。
