[Insufficient formation of interferon in children with recurrent respiratory infections].

The authors investigated the ability of IFN-alpha formation in 50 children followed up on account of frequent and relapsing respiratory diseases. The ability to produce IFN-alpha was consistent with the clinical condition. Children who were frequently ill and whose condition did not improve during the last two years had an inadequate IFN-alpha production. Conversely, children whose health status improved substantially during the follow up period or those who were considered cured had a normal IFN-alpha production. Influencing of the IFN-alpha production might have a favourable effect on the clinical course of the disease.