反复呼吸道感染患儿中干扰素-α产生缺陷。原发性还是继发性缺陷？
Defective interferon-alpha production in children with recurrent respiratory tract infections. A primary or secondary deficiency?
作者信息
Pugliese A, Salomone C, Martino S, Biglino A, Delpiano A, Tovo P A
出版信息
Boll Ist Sieroter Milan. 1985;64(4):328-31.
PMID:4074516
Abstract
Interferon-alpha and -gamma production was assayed in 44 children with recurrent respiratory tract infections, in 9 patients with recurrent stomatitis and in 32 control subjects. A partial, transitory deficiency in interferon-alpha production was found in 2 children with recurrent respiratory tract infections. The deficiency may be either cause or effect of the recurrent infections. Many data support the latter hypothesis.
摘要
对44名复发性呼吸道感染儿童、9名复发性口腔炎患者和32名对照受试者进行了α干扰素和γ干扰素产生情况的检测。在2名复发性呼吸道感染儿童中发现了α干扰素产生的部分、暂时性缺陷。这种缺陷可能是复发性感染的原因或结果。许多数据支持后一种假设。
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