Maskos K
Acta Biochim Pol. 1978;25(4):311-23.
The interaction of copper(II) with adenosine, 2'-deoxyadenosine, 1-methyladenosine, 7-deazaadenosine and AMP was studied by spectroscopic and magnetochemical methods. In non-aqueous medium, copper(II) interacts with adenosine and AMP at N-7 and N-1, and with 1-methyladenosine at N-7 and N-3. The copper ion is not bound to the NH2 group. In aqueous solution, copper(II) interacts both with N-7 and N-1 of adenosine, and in AMP additionally with the phosphate group. The interaction of copper(II) with the heterocyclic part, but not withthe phosphate group, is dependent on the extent of protonation of the molecular. A crystalline AMP-copper(II) complex [Cu(C10H12N5O7P).(H2O)2] was obtained; the phosphate group and probably N-7 are involved in the complex formation.
通过光谱和磁化学方法研究了铜（II）与腺苷、2'-脱氧腺苷、1-甲基腺苷、7-脱氮腺苷和AMP的相互作用。在非水介质中，铜（II）在N-7和N-1处与腺苷和AMP相互作用，在N-7和N-3处与1-甲基腺苷相互作用。铜离子不与NH2基团结合。在水溶液中，铜（II）与腺苷的N-7和N-1相互作用，在AMP中还与磷酸基团相互作用。铜（II）与杂环部分而非磷酸基团的相互作用取决于分子的质子化程度。得到了一种结晶的AMP-铜（II）配合物[Cu(C10H12N5O7P)·(H2O)2]；磷酸基团以及可能的N-7参与了配合物的形成。
