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Studies on cardiotonic agents. I. Synthesis of some quinazoline derivatives.

作者信息

Nomoto Y, Obase H, Takai H, Hirata T, Teranishi M, Nakamura J, Kubo K

机构信息

Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd., Japan.

出版信息

Chem Pharm Bull (Tokyo). 1990 Jun;38(6):1591-5. doi: 10.1248/cpb.38.1591.

DOI:10.1248/cpb.38.1591
PMID:2208370
Abstract

A series of quinazoline derivatives with various 4-heterocyclylpiperidino groups at the 4-position was synthesized and tested for cardiotonic activity in anesthetized dogs. Among them, several 6,7-dimethoxyquinazoline derivatives showed potent cardiotonic activity.

摘要

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