Wu Y
First Affiliated Hospital of Nanjing Medical College.
Zhong Xi Yi Jie He Za Zhi. 1990 Jul;10(7):395-8, 387.
Two hundred and sixty seven cases of angina pectoris of coronary heart disease (male 152, female 115, age 41--79) were studied. Among these, 195 cases were patients with effort angina, 72 cases with non-effort angina. Double blind stratified randomized grouping, differentiation- syndromes treatment of TCM and self-control observation methods were applied. The results showed that total effective rate was 93.3% for angina pectoris in the treatment group. While control group which were treated by persantin and aspirin was 54.7% (P less than 0.001). For resting ECG evaluation total effective rates were 52.78% and 13.51% respectively. The ECG exercise testing (protocol Bruce) and dynamic ECG also showed the results similar to that of resting ECG. According to differentiation-syndromes treatment of TCM. The effect of Xintongkang capsule on simple stagnation of Qi and stasis of blood, or combined with deficiency of Qi, or combined with deficiency of Yin was better than other symptoms. The effect of Xintongkang capsule initiated in the second week after oral medicine, peak response occurring in the fourth week, and it trend to the stability in the eighth week. There was no harmful effect to heart, liver, kidney and blood. No allergic reactions were found in this observation.
对267例冠心病心绞痛患者（男152例，女115例，年龄41 - 79岁）进行了研究。其中，劳力性心绞痛患者195例，非劳力性心绞痛患者72例。采用双盲分层随机分组、中医辨证论治及自身对照观察方法。结果显示，治疗组心绞痛总有效率为93.3%。而用潘生丁和阿司匹林治疗的对照组总有效率为54.7%（P<0.001）。静息心电图评价总有效率分别为52.78%和13.51%。心电图运动试验（Bruce方案）及动态心电图结果与静息心电图相似。根据中医辨证论治，心痛康胶囊对单纯气滞血瘀、或兼气虚、或兼阴虚的疗效优于其他证型。心痛康胶囊口服后第二周开始起效，第四周出现疗效高峰，第八周趋于稳定。对心、肝、肾及血液无不良影响。本观察未发现过敏反应。
