Li Q J, Duan J H, Hu G L, Yu L R, Yang W Q, Li L Z, Ouyang H K
Sanitary and Anti-Epidemic Station of Hunan Province.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1990;8(2):134-7.
Of 98 counties or cities in Hunan Province, 55 were endemic areas of filariasis. The average microfilaria rate was 5.64% (180,046/3,194,102), and the incidence of advanced filariasis, including elephantiasis and hydrocele was 3.29%. The number of filariasis patients in the whole province was estimated to be 1.63 million, comprising 1.25 million of microfilaremia cases, Culex fatigans and Anopheles hyrcanus sinensis were the major vectors of bancroftian and malayan filariasis respectively in the province. Control strategies concentrated on the elimination of infection source were implemented on the basis of extensive investigations, and the ensuing examination and treatment of filariasis cases in pilot areas prior to the implementation of province-wide filariasis control. Repeated blood examinations and medications for 3-4 times were carried out in hypo-endemic areas of malayan filariasis, whereas mass treatment with hetrazan-medicated salt containing 0.2% to 0.5% DEC was carried out in meso- and hyper-endemic areas of bancroftian filariasis as well as those situated in remote mountainous regions for six months. Subsequent evaluation and clearance checking showed that microfilaria rate of the whole province has already dropped to less than 1%. That filariasis was basically eliminated in Hunan was recognized by the Evaluation Mission Group sent by the Ministry of Public Health in 1986.
湖南省98个县(市)中,有55个为丝虫病流行区。平均微丝蚴率为5.64%(180,046/3,194,102),晚期丝虫病(包括象皮肿和鞘膜积液)发病率为3.29%。全省丝虫病患者估计有163万,其中微丝蚴血症患者125万,致倦库蚊和中华按蚊分别是该省班氏丝虫病和马来丝虫病的主要传播媒介。在广泛调查的基础上,实施了以消灭传染源为主的防治策略,并在全省开展丝虫病防治工作之前,先在试点地区对丝虫病患者进行检查和治疗。在马来丝虫病低度流行区进行3 - 4次反复血液检查和药物治疗,而在班氏丝虫病中度和高度流行区以及偏远山区,用含0.2%至0.5%乙胺嗪的海群生药盐进行6个月的全民治疗。随后的评估和清理检查表明,全省微丝蚴率已降至1%以下。1986年,卫生部派出的考核组确认湖南丝虫病已基本消灭。