使用血清胆固醇/甘油三酯比值来辨别哪些个体可以放心使用弗里德瓦尔德公式。
Use of serum cholesterol/triglyceride ratio to discern for which individuals the Friedewald formula can be used confidently.
作者信息
González Estrada M, Rodríguez Ferrer C R, Astarloa I R, Lahera E M
机构信息
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of La Laguna, Canary Islands, Spain.
出版信息
Clin Chem. 1990 Sep;36(9):1673-5.
The values of low-density lipoprotein cholesterol obtained according to the Friedewald formula (Clin Chem 1972; 18:499-502), or by the De Long transformation (J Am Med Assoc 1986;256:2372-7), were compared with the values obtained when the individual cholesterol/triglyceride ratio of very-low-density lipoprotein was used for estimating the contribution of this lipoprotein to the total cholesterol. We found that these formulas gave the greatest errors for individuals with a low serum cholesterol/triglyceride ratio. We propose criteria for deciding when the numerically calculated value of low-density cholesterol is appropriate, and when it is not.
根据Friedewald公式（《临床化学》1972年；第18卷：499 - 502页）或De Long转换法（《美国医学会杂志》1986年；256卷：2372 - 2377页）获得的低密度脂蛋白胆固醇值，与使用极低密度脂蛋白的个体胆固醇/甘油三酯比率来估算该脂蛋白对总胆固醇的贡献时所获得的值进行了比较。我们发现，对于血清胆固醇/甘油三酯比率较低的个体，这些公式产生的误差最大。我们提出了判定低密度胆固醇的数值计算何时合适、何时不合适的标准。
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