来自海洋无脊椎动物的具有抗肿瘤功效的生物活性物质：苔藓虫纲、软体动物门、棘皮动物门和尾索动物亚门。
Bioactive substances with anti-neoplastic efficacy from marine invertebrates: Bryozoa, Mollusca, Echinodermata and Urochordata.
作者信息
Sima Peter, Vetvicka Vaclav
机构信息
Peter Sima, Institute of Microbiology, Czech Academy of Sciences, 142 20 Prague 15400, Czech Republic.
出版信息
World J Clin Oncol. 2011 Nov 10;2(11):362-6. doi: 10.5306/wjco.v2.i11.362.
The marine environment provides a rich source of natural products with potential therapeutic application. This has resulted in an increased rate of pharmaceutical agents being discovered in marine animals, particularly invertebrates. Our objective is to summarize the most promising compounds which have the best potential and may lead to use in clinical practice, show their biological activities and highlight the compounds currently being tested in clinical trials. In this paper, we focused on Bryozoa, Mollusca, Echinodermata and Urochordata.
海洋环境提供了丰富的具有潜在治疗应用价值的天然产物来源。这导致从海洋动物，特别是无脊椎动物中发现药物制剂的速率有所增加。我们的目标是总结最有前景、具有最佳潜力且可能用于临床实践的化合物，展示它们的生物活性，并突出目前正在临床试验中进行测试的化合物。在本文中，我们重点关注苔藓虫纲、软体动物门、棘皮动物门和尾索动物亚门。
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