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经皮胆囊造口术治疗高危患者急性胆囊炎的近期和远期疗效。

Short- and long-term outcomes following percutaneous cholecystostomy for acute cholecystitis in high-risk patients.

机构信息

Department of Surgery, Health Sciences Centre, University of Manitoba, GF-431, 820 Sherbrook Street, Winnipeg, MB, R3A 1R9, Canada.

出版信息

Surg Endosc. 2012 May;26(5):1343-51. doi: 10.1007/s00464-011-2035-0. Epub 2011 Nov 17.

Abstract

BACKGROUND

Percutaneous cholecystostomy is a less invasive method to treat acute cholecystitis in patients who are critically ill or have serious medical comorbidities precluding the use of general anesthesia. It remains controversial whether interval cholecystectomy is warranted. The objectives of the study were to determine the success rate and complications of percutaneous cholecystostomy and the proportion of patients without recurrent attacks in whom interval cholecystectomy was not needed.

METHODS

This was a retrospective review to determine the outcomes after percutaneous cholecystostomy for acute calculous cholecystitis between 1995 and 2007. Administrative data were used to better capture recurrent symptoms requiring treatment.

RESULTS

Sixty-eight patients with a mean age of 74 years were identified. Sixty-seven (98.5%) underwent successful insertion of the cholecystostomy tubes. Eleven patients suffered tube-related complications, including tube dislodgment (9), tube blockage (1), and bleeding that was controlled with conservative management (1). The initial episode of cholecystitis was treated successfully in 58 patients (85%). The overall in-hospital and 30-day mortality were both 15% (10 patients). A total of 7 patients (10%) underwent cholecystectomy while still in hospital. There were 39 patients at risk for recurrent disease who survived the initial episode and did not receive an interval cholecystectomy. Of these 39 patients, 16 (41%) suffered recurrent gallbladder-related disease.

CONCLUSIONS

Percutaneous cholecystostomy is an alternative to cholecystectomy in patients with acute calculous cholecystitis who are at high risk for surgical mortality and morbidity. It appears to have a low complication rate and good clinical success. Because a significant number of patients suffer recurrent attacks, elective cholecystectomy should be considered routinely. Unfortunately, firm criteria for selecting percutaneous cholecystostomy over cholecystectomy are lacking, and the surgeon's clinical judgment is critically important.

摘要

背景

经皮胆囊造口术是一种微创方法,适用于因病情危重或存在严重合并症而不能接受全身麻醉的急性胆囊炎患者。对于是否需要行间隔期胆囊切除术,目前仍存在争议。本研究旨在确定经皮胆囊造口术的成功率和并发症,以及不需要间隔期胆囊切除术的患者中无复发发作的比例。

方法

本研究为回顾性研究,旨在确定 1995 年至 2007 年期间经皮胆囊造口术治疗急性结石性胆囊炎的结果。采用行政数据更好地捕捉需要治疗的复发性症状。

结果

共纳入 68 例平均年龄为 74 岁的患者。67 例(98.5%)患者成功插入胆囊造口管。11 例患者发生与导管相关的并发症,包括导管移位(9 例)、导管堵塞(1 例)和出血(1 例),经保守治疗得到控制。58 例(85%)患者的初始胆囊炎发作得到成功治疗。总的住院和 30 天死亡率均为 15%(10 例)。共有 7 例(10%)患者在住院期间行胆囊切除术。39 例患者在初始发作后存活且未接受间隔期胆囊切除术,存在发生复发性疾病的风险。这 39 例患者中,16 例(41%)患有复发性胆囊相关疾病。

结论

对于手术死亡率和发病率高的急性结石性胆囊炎患者,经皮胆囊造口术是胆囊切除术的替代方法。它似乎具有较低的并发症发生率和良好的临床成功率。由于相当数量的患者发生复发性发作,应常规考虑择期胆囊切除术。不幸的是,目前缺乏选择经皮胆囊造口术而非胆囊切除术的明确标准,外科医生的临床判断至关重要。

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