Smith Kevin C
Skin Therapy Lett. 2011 Sep;16(8):3-6.
Now that several formulations of botulinum toxin type-A (BoNT-A) are on the market in North America and throughout the world, it is of great practical importance for those who administer these medications to be familiar with the differences between the formulations. These differences pertain to the stability of the medications, in particular during the period of time between reconstitution and administration, which may affect the degree of diffusion through various tissues after injection. A variety of relatively new uses of BoNT-A for dermatological conditions will be discussed.
鉴于A型肉毒杆菌毒素（BoNT-A）的几种制剂已在北美和全球上市，对于使用这些药物的人员来说，熟悉不同制剂之间的差异具有重大的实际意义。这些差异与药物的稳定性有关，尤其是在复溶和给药之间的时间段内，这可能会影响注射后药物在各种组织中的扩散程度。本文将讨论BoNT-A在皮肤病治疗方面的各种相对较新的用途。
