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Vitamin B₁₂ deficiency & cognitive impairment in elderly population.

作者信息

Agarwal Rachna

机构信息

Department of Neurochemistry, Institute of Human Behaviour & Allied Sciences Jhilmil, Dilshad Garden, Delhi 110 095, India.

出版信息

Indian J Med Res. 2011 Oct;134(4):410-2.

PMID:22089600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3237236/
Abstract
摘要

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Vitamin B₁₂ deficiency & cognitive impairment in elderly population.老年人群中的维生素B₁₂缺乏与认知障碍
Indian J Med Res. 2011 Oct;134(4):410-2.
2
Vitamin B₁₂ deficiency & levels of metabolites in an apparently normal urban south Indian elderly population.貌似健康的印度南部城市老年人群中维生素 B₁₂ 缺乏及代谢物水平。
Indian J Med Res. 2011 Oct;134(4):432-9.
3
Vitamin B-12 deficiency in the elderly: current dilemmas.老年人维生素B-12缺乏：当前的困境
Am J Clin Nutr. 1997 Oct;66(4):741-9. doi: 10.1093/ajcn/66.4.741.
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Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.高同型半胱氨酸血症和甲基丙二酸水平升高表明亚洲印度人维生素B12缺乏症的患病率很高。
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Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged.肾功能损害会影响总同型半胱氨酸和甲基丙二酸的检测结果，但不会影响总维生素B12和全转钴胺素在老年人维生素B12缺乏筛查中的应用。
Clin Chem Lab Med. 2007;45(2):197-201. doi: 10.1515/CCLM.2007.028.
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Nutritional Supplementation with Chlorella pyrenoidosa Lowers Serum Methylmalonic Acid in Vegans and Vegetarians with a Suspected Vitamin B₁₂ Deficiency.小球藻营养补充剂可降低疑似维生素B₁₂缺乏的纯素食者和素食者的血清甲基丙二酸水平。
J Med Food. 2015 Dec;18(12):1357-62. doi: 10.1089/jmf.2015.0056. Epub 2015 Oct 20.
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Methylmalonic acid and homocysteine assessment in the detection of vitamin B12 deficiency in patients with bilateral visual loss.甲基丙二酸和同型半胱氨酸评估在双侧视力丧失患者维生素B12缺乏检测中的应用
Acta Ophthalmol. 2012 May;90(3):e252-3. doi: 10.1111/j.1755-3768.2011.02342.x. Epub 2012 Jan 23.
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Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cobalamin.血清钴胺素水平较低的老年受试者的钴胺素吸收、血清同型半胱氨酸和甲基丙二酸
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High prevalence of cobalamin deficiency in elderly outpatients.老年门诊患者中钴胺素缺乏的高患病率。
J Am Geriatr Soc. 1992 Dec;40(12):1197-204.
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Methylmalonic acid: a test whose time has come?
Arch Pathol Lab Med. 2001 Jun;125(6):824-7. doi: 10.5858/2001-125-0824-MA.

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本文引用的文献

1
Vitamin B₁₂ deficiency & levels of metabolites in an apparently normal urban south Indian elderly population.貌似健康的印度南部城市老年人群中维生素 B₁₂ 缺乏及代谢物水平。
Indian J Med Res. 2011 Oct;134(4):432-9.
2
Role of vitamin B(12), folate, and thyroid stimulating hormone in dementia: A hospital-based study in north Indian population.维生素B12、叶酸和促甲状腺激素在痴呆症中的作用：一项基于印度北部人群的医院研究。
Ann Indian Acad Neurol. 2010 Oct;13(4):257-62. doi: 10.4103/0972-2327.74193.
3
Low folate levels in the cognitive decline of elderly patients and the efficacy of folate as a treatment for improving memory deficits.老年患者认知功能衰退中叶酸水平较低以及叶酸作为改善记忆缺陷治疗方法的疗效。
Arch Gerontol Geriatr. 1998 Jan-Feb;26(1):1-13. doi: 10.1016/s0167-4943(97)00028-9.
4
Vitamin B12 deficiency and hyperhomocysteinemia in rural and urban Indians.印度城乡居民维生素B12缺乏与高同型半胱氨酸血症
J Assoc Physicians India. 2006 Oct;54:775-82.
5
Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial.口服维生素B12联合或不联合叶酸对轻度维生素B12缺乏的老年人认知功能的影响：一项随机、安慰剂对照试验。
Am J Clin Nutr. 2006 Aug;84(2):361-70. doi: 10.1093/ajcn/84.1.361.
6
No effect of vitamin B-12 treatment on cognitive function and depression: a randomized placebo controlled study.维生素B-12治疗对认知功能和抑郁无影响：一项随机安慰剂对照研究。
J Affect Disord. 2004 Sep;81(3):269-73. doi: 10.1016/S0165-0327(03)00169-1.
7
Nutrition and cognitive impairment in the elderly.老年人的营养与认知障碍
Br J Nutr. 2001 Sep;86(3):313-21. doi: 10.1079/bjn2001388.
8
Vitamin B(12) and folate in relation to the development of Alzheimer's disease.维生素B12和叶酸与阿尔茨海默病的发展
Neurology. 2001 May 8;56(9):1188-94. doi: 10.1212/wnl.56.9.1188.
9
Early diagnosis of cognitive impairment in the elderly with the focus on Alzheimer's disease.以阿尔茨海默病为重点的老年人认知障碍早期诊断
J Neural Transm (Vienna). 1998;105(8-9):773-86. doi: 10.1007/s007020050094.
10
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.确诊阿尔茨海默病患者的叶酸、维生素B12及血清总同型半胱氨酸水平
Arch Neurol. 1998 Nov;55(11):1449-55. doi: 10.1001/archneur.55.11.1449.