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桥本甲状腺炎的细针穿刺细胞学检查——诊断陷阱及文献综述

Fine needle aspiration cytology of Hashimoto's thyroiditis - A diagnostic pitfall with review of literature.

作者信息

Gayathri Bn, Kalyani R, Harendra Kumar Ml, Krishna Prasad K

机构信息

Department of Pathology, SDUMC, Kolar, Karnataka, India.

出版信息

J Cytol. 2011 Oct;28(4):210-3. doi: 10.4103/0970-9371.86353.

Abstract

Hashimoto's thyroiditis is the second most common thyroid lesion next to goiter diagnosed on fine needle aspiration cytology (FNAC). It is also an important cause for hypothyroidism. FNAC plays a significant role in the diagnosis of thyroid lesions due to its simplicity and low cost. It can accurately diagnose Hashimoto's thyroidits in most patients. However, a small percentage of cases may be missed due to the inherent limitations of this procedure and the varied cytomorphology of this lesion. Therefore thorough cytological evaluation and an integrated approach are necessary to pick up correct diagnosis and to avoid unnecessary surgery. We present a 56-year-old female with solitary thyroid nodule diagnosed as Hurthle cell neoplasm on FNAC, but subsequent histopathological diagnosis following resection revealed Hashimoto's thyroiditis with marked Hurthle cell change.

摘要

桥本甲状腺炎是细针穿刺抽吸活检(FNAC)诊断出的仅次于甲状腺肿的第二常见甲状腺病变。它也是甲状腺功能减退的一个重要原因。FNAC因其操作简单且成本低,在甲状腺病变的诊断中发挥着重要作用。它能在大多数患者中准确诊断出桥本甲状腺炎。然而,由于该检查方法的固有局限性以及此病变多样的细胞形态,仍有一小部分病例可能被漏诊。因此,进行全面的细胞学评估并采用综合方法对于做出正确诊断以及避免不必要的手术是必要的。我们报告一名56岁女性,其甲状腺单发结节在FNAC上被诊断为许特耳细胞肿瘤,但切除后的后续组织病理学诊断显示为桥本甲状腺炎伴显著的许特耳细胞改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf26/3214470/fa9b85e1b306/JCytol-28-210-g001.jpg

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