Deb Prabal, Kinra Prateek, Bhatoe Harjinder Singh
Department of Pathology, Armed Forces Medical College, Pune, India.
J Cytol. 2011 Oct;28(4):219-22. doi: 10.4103/0970-9371.86357.
Central neurocytomas (CNs) are uncommon tumors of the central nervous system. These tumors have a predilection for the lateral ventricles of young adults and are known to display characteristic neuroimaging and histomorphologic features. Typically, CNs are associated with a favorable outcome, although cases with more aggressive clinical course with recurrences are not unknown. Most descriptions of this tumor are available in the form of isolated histopathology-based case reports and small series. Cytology-based publications of CN are rare. Here, we report a case of CN in a 22-year-old girl. Intra-operative squash cytology and subsequent histopathology of the tumor simulated an oligodendroglioma and a clear cell ependydoma. Final confirmation was obtained on immunohistochemistry. This paper discusses the salient cytological, histomorphological and immunohistochemical features of CN that are useful in distinguishing from its mimickers.
中枢神经细胞瘤（CNs）是中枢神经系统的罕见肿瘤。这些肿瘤好发于年轻成人的侧脑室，已知具有特征性的神经影像学和组织形态学特征。通常，CNs预后良好，不过临床病程更具侵袭性且有复发的病例也并非罕见。关于这种肿瘤的大多数描述是以基于组织病理学的孤立病例报告和小系列研究的形式呈现。基于细胞学的CNs出版物很少见。在此，我们报告一例22岁女孩的CNs病例。肿瘤的术中压片细胞学检查及随后的组织病理学检查结果类似少突胶质细胞瘤和透明细胞室管膜瘤。最终通过免疫组化得以确诊。本文讨论了CNs的显著细胞学、组织形态学和免疫组化特征，这些特征有助于将其与相似肿瘤相鉴别。
