Lustenberger Thomas, Meier Christoph, Benninger Emanuel, Lenzlinger Philipp M, Keel Marius J B
Departments of Trauma, Hand and Reconstructive Surgery, University Hospital, Goethe University, Frankfurt am Main, Germany.
J Emerg Trauma Shock. 2011 Oct;4(4):477-82. doi: 10.4103/0974-2700.86632.
Exsanguinating hemorrhage is the major cause of death in patients with pelvic ring disruption.
The aim of this study was to document outcomes after the stabilization of pelvic ring injuries by a C-clamp and control of hemorrhage by pelvic packing. Physiological parameters were tested as prognostic factors.
This was a retrospective study at a level I trauma center. The study period was from January 1996 to December 2007.
Fifty patients with pelvic ring disruption and hemorrhagic shock were analyzed. The pelvic rings were fixed by a C-clamp, and patients with ongoing hemorrhage underwent laparotomy and extra- and/or intra-peritoneal pelvic packing. Clinical parameters (heart rate, mean arterial pressure) and physiological parameters (lactate levels, hemoglobin, hematocrit) were documented at admission and at different time points during the initial treatment (1, 2, 3, 4, 6, 8, and 12h after admission).
Within 12 h of admission, 16 patients died (nonsurvivors) due to hemorrhagic shock (n=13) or head injuries (n=3). In this group, 12 patients underwent laparotomy with pelvic packing. Thirty-four patients survived the first 12 h (early survivors) after fixation by a C-clamp and additional packing in 23 patients. Four of these patients died 12.3±7.1 days later due to multiple organ failure (n=3) or severe head injury (n=1). The blood lactate level at admission was significantly higher in the group of nonsurvivors (7.2±0.8 mmol/L) compared to the early survivors (4.3±0.5 mmol/L, P<0.05). While hemoglobin values improved within the first 2 h in nonsurvivors, lactate levels continued to increase.
Pelvic packing in addition to the C-clamp fixation effectively controls severe hemorrhage in patients with pelvic ring disruption. Early sequential measurements of blood lactate levels can be used to estimate the severity of shock and the response to the shock treatment.
失血性出血是骨盆环骨折患者死亡的主要原因。
本研究的目的是记录通过C形夹稳定骨盆环损伤并通过骨盆填塞控制出血后的结果。将生理参数作为预后因素进行测试。
这是一项在一级创伤中心进行的回顾性研究。研究期间为1996年1月至2007年12月。
分析50例骨盆环骨折并失血性休克患者。用C形夹固定骨盆环,持续出血的患者接受剖腹手术及腹膜外和/或腹膜内骨盆填塞。记录入院时及初始治疗期间不同时间点(入院后1、2、3、4、6、8和12小时)的临床参数(心率、平均动脉压)和生理参数(乳酸水平、血红蛋白、血细胞比容)。
入院12小时内,16例患者(非幸存者)因失血性休克(n = 13)或头部损伤(n = 3)死亡。该组中,12例患者接受了剖腹手术及骨盆填塞。34例患者在通过C形夹固定及23例患者额外填塞后存活了最初12小时(早期幸存者)。其中4例患者在12.3±7.1天后因多器官功能衰竭(n = 3)或严重头部损伤(n = 1)死亡。与早期幸存者(4.3±0.5 mmol/L)相比,非幸存者入院时的血乳酸水平显著更高(7.2±0.8 mmol/L,P<0.05)。非幸存者的血红蛋白值在最初2小时内有所改善,而乳酸水平持续升高。
除C形夹固定外,骨盆填塞可有效控制骨盆环骨折患者的严重出血。早期连续测量血乳酸水平可用于评估休克的严重程度及对休克治疗的反应。