Department of Psychiatry and Pediatrics, Johns Hopkins University School of Medicine , Kennedy Krieger Research Institute, Baltimore, Maryland 21224, USA.
J Neurotrauma. 2012 Mar 1;29(4):621-8. doi: 10.1089/neu.2011.2234. Epub 2012 Jan 17.
This article builds upon Traumatic Brain Injury Common Data Elements (TBI CDE) version 1.0 and the pediatric CDE Initiative by emphasizing the essential role of psychosocial risk and protective factors in pediatric TBI research. The goals are to provide a compelling rationale for including psychosocial risk and protective factors in addition to socioeconomic status (SES), age, and sex in the study design and analyses of pediatric TBI research and to describe recommendations for core common data elements in this domain. Risk and protective factor research is based on the ecological theory of child development in which children develop through a series of interactions with their immediate and more distant environments. Home, school, religious, and social influences are conceptualized as risk and/or protective factors. Child development and TBI researchers have interpreted risk and protective variables as main effects or as interactions and have used cumulative risk indices and moderation models to describe the relationship among these variables and outcomes that have to do with development and with recovery from TBI. It is likely that the number, type, and interaction among risk and protective factors each contribute unique variance to study outcomes. Longitudinal designs in TBI research will be essential to understanding the reciprocal relationships between risk/protective factors and the recovery/outcome made by the child. The search for effective interventions to hasten TBI recovery mandates the need to target modifiable risks and to promote protective factors in the child's environment.
本文基于创伤性脑损伤通用数据元素(TBI CDE)版本 1.0 和儿科 CDE 计划,强调了心理社会风险和保护因素在儿科 TBI 研究中的重要作用。目标是为在儿科 TBI 研究的设计和分析中除了社会经济地位(SES)、年龄和性别之外,纳入心理社会风险和保护因素提供有力的理由,并描述该领域核心通用数据元素的建议。风险和保护因素研究基于儿童发展的生态理论,儿童通过与直接和更遥远的环境的一系列相互作用而发展。家庭、学校、宗教和社会影响被概念化为风险和/或保护因素。儿童发展和 TBI 研究人员将风险和保护变量解释为主要效应或相互作用,并使用累积风险指数和调节模型来描述这些变量与与发展和 TBI 恢复有关的结果之间的关系。风险和保护因素之间的数量、类型和相互作用可能都对研究结果有独特的影响。TBI 研究中的纵向设计对于理解风险/保护因素与儿童恢复/结果之间的相互关系至关重要。为了寻找有效的干预措施来加速 TBI 的恢复,有必要针对可改变的风险,并在儿童的环境中促进保护因素。