Wu Z C, Jiang X J
Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1990 Jul;24(4):196-8.
Under defined conditions, E. coli bacteriophage f2 was subject to repeated disinfection by chlorine 10 times. The survival bacteriophage f2 was compared with its original strain in resistance to chlorine. Experimental results showed that bacteriophage f2 increased its resistance after chlorine disinfection. The increased resistance varied under different conditions. The higher the pH, the greater the increased resistance. The survival bacteriophage f2 maintained its increased resistance though it was passaged 10 times in nutrient broth. The reason for the increased resistance of bacteriophage f2 after chlorine disinfection was probably the chlorine-induced mutation or spontaneous chlorine-resistant mutation.
在特定条件下，大肠杆菌噬菌体f2接受了10次氯的反复消毒。将存活的噬菌体f2与其原始菌株在氯抗性方面进行了比较。实验结果表明，噬菌体f2在氯消毒后抗性增强。不同条件下抗性增强程度不同。pH值越高，抗性增强越大。存活的噬菌体f2尽管在营养肉汤中传代10次，仍保持其增强的抗性。噬菌体f2在氯消毒后抗性增强的原因可能是氯诱导的突变或自发的耐氯突变。
