Division of Mohs Micrographic Surgery, Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA.
Dermatol Surg. 2011 Dec;37(12):1740-6. doi: 10.1111/j.1524-4725.2011.02166.x. Epub 2011 Sep 14.
Postsurgical scars are of significant concern to patients and surgeons. Many studies have focused on different treatment options for established surgical scars. The prevention and minimization of such aberrant healing responses is more likely to yield better outcomes and require less time and expense.
A review of the literature on various forms of prophylactic treatments intended to prevent or minimize the development of prominent postsurgical scars was performed using the Pubmed database over a period from 1987 to 2010. Search terms included "scar prevention," "scar minimization," "post-surgical scar management," and "surgical scars."
Various over-the-counter topical products commonly used by patients have failed to demonstrate any significant benefits in improving final scar outcomes. Numerous interventions performed around the time of surgery, including botulinum toxin, lasers, and intradermal injectable products, have shown effectiveness in minimizing eventual scar appearance.
Patient education on proper wound care is a simple method of improving the cosmetic appearance of surgical scars. At the other end of the spectrum, our knowledge of the complex mechanisms of wound healing has allowed for the development of new, effective treatment modalities, including lasers, botulinum toxin, cytokines, and stem cells.
术后疤痕是患者和外科医生非常关注的问题。许多研究都集中在已建立的手术疤痕的不同治疗选择上。预防和最小化这种异常愈合反应更有可能产生更好的结果，并且需要更少的时间和费用。
使用 Pubmed 数据库，检索了从 1987 年到 2010 年期间关于各种预防治疗方法的文献，旨在预防或最小化明显的术后疤痕的形成。检索词包括“疤痕预防”、“疤痕最小化”、“术后疤痕管理”和“手术疤痕”。
患者常用的各种非处方外用产品在改善最终疤痕结果方面均未显示出任何显著益处。许多在手术时进行的干预措施，包括肉毒毒素、激光和皮内注射产品，已显示出在最小化最终疤痕外观方面的有效性。
对患者进行适当伤口护理的教育是改善手术疤痕美容外观的简单方法。在另一个极端，我们对伤口愈合复杂机制的认识使新的、有效的治疗方法得以发展，包括激光、肉毒毒素、细胞因子和干细胞。
