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化学固定在改善瘢痕修复手术效果中的作用

The Role of Chemoimmobilization in Improving the Outcome of Scar Revision Surgery.

作者信息

Chandraiah Madura, Siddappa Harsha, Shenoy Chaithra, Ramachandra Kusuma Margonahalli, Jayaram Dinesh, Chandrashekar Byalakere Shivanna

机构信息

Department of Dermatosurgery, Vijayanagar, Bangalore, India.

Aesthetic Dermatology, Bangalore, India.

出版信息

J Cutan Aesthet Surg. 2022 Oct-Dec;15(4):381-386. doi: 10.4103/JCAS.JCAS_56_21.

Abstract

BACKGROUND

The major goal of scar revision is to make the scar aesthetically more acceptable. The injection of botulinum toxin type A is known to help in improving the outcomes of scars by reducing the tension across the wound edges and by promoting better wound healing.

OBJECTIVE

The aim of this article is to evaluate the efficacy of botulinum toxin injection following scar revision surgeries.

MATERIALS AND METHODS

A prospective, comparative study involving 20 patients with post-traumatic scars over the face was conducted between July 2018 and July 2019. The patients were divided into two groups: group A underwent scar revision surgery followed by BTX injection on the day of suture removal and group B underwent scar revision surgery alone. The photographic assessment was done at the end of a 1-year follow-up, by three blind investigators based on a pre-designed scale to grade improvement.

RESULTS

The average grade of improvement of group A (3.02±1.1) was significantly higher when compared with that of group B (2.1±0.8) ( = 0.001).

CONCLUSION

This study demonstrates that the combination treatment of scar revision with BTX injection is very effective in producing aesthetically better scars.

摘要

背景

瘢痕修复的主要目标是使瘢痕在美学上更易被接受。已知注射A型肉毒杆菌毒素有助于改善瘢痕的治疗效果,其作用机制为降低伤口边缘的张力并促进伤口更好地愈合。

目的

本文旨在评估瘢痕修复手术后注射肉毒杆菌毒素的疗效。

材料与方法

2018年7月至2019年7月,对20例面部有创伤后瘢痕的患者进行了一项前瞻性对照研究。患者被分为两组:A组在拆线当天接受瘢痕修复手术,随后注射肉毒杆菌毒素;B组仅接受瘢痕修复手术。在1年随访结束时,由3名盲法研究者根据预先设计的量表对改善情况进行分级,进行照片评估。

结果

A组的平均改善等级(3.02±1.1)显著高于B组(2.1±0.8)(P = 0.001)。

结论

本研究表明,瘢痕修复联合注射肉毒杆菌毒素的联合治疗在产生美学效果更好的瘢痕方面非常有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ba1/10081473/579f844cd316/JCAS-15-381-g001.jpg

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