Department of Internal Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
Br J Nutr. 2012 Sep;108(5):910-7. doi: 10.1017/S0007114511006118. Epub 2011 Nov 18.
As part of a feasibility study to prevent gestational diabetes mellitus (GDM), we evaluated the effect of an intensive dietary therapy on quality of diet, weight gain and birth weight in women at high risk of GDM. Women with risk factors for GDM (n 54) were randomly assigned from April 2005 to May 2006 to a lifestyle intervention group (n 27) including dietary advice six times during pregnancy or to a close follow-up group (n 27) in a community-based setting in Finland. Dietary intake was recorded three times during pregnancy using 4 d food records. The main outcome was the incidence of GDM. The secondary outcomes were the changes in nutrient intake, weight gain and birth weight. Overall, seventeen (65 %) women in the intervention group and eighteen (69 %) women in the close follow-up group returned all three food records. PUFA intake increased (P = 0·008) during pregnancy in the intervention as compared to the close follow-up group. There were no clear differences in the changes of saturated fat or fibre intake between the groups. Intensive dietary education resulted in a somewhat lower weight gain during pregnancy (P = 0·062) and higher birth weights of the infants (P = 0·047) without an effect on macrosomia as compared to the close follow-up group. Individualised counselling by a clinical nutritionist as part of a lifestyle intervention improved the quality of dietary fat intake in pregnant women at high risk of GDM.
作为预防妊娠糖尿病(GDM)可行性研究的一部分,我们评估了强化饮食疗法对 GDM 高危妇女饮食质量、体重增加和出生体重的影响。2005 年 4 月至 2006 年 5 月,芬兰社区内将具有 GDM 危险因素的女性(n=54)随机分为生活方式干预组(n=27,包括孕期 6 次饮食建议)或密切随访组(n=27)。在妊娠期间,通过 4 天的食物记录三次记录饮食摄入量。主要结局是 GDM 的发生率。次要结局是营养素摄入、体重增加和出生体重的变化。总体而言,干预组 17 名(65%)女性和密切随访组 18 名(69%)女性返回了所有三份食物记录。与密切随访组相比,干预组的多不饱和脂肪酸(PUFA)摄入在妊娠期间增加(P=0·008)。两组之间饱和脂肪或纤维摄入的变化没有明显差异。强化饮食教育导致妊娠期间体重增加略低(P=0·062),且婴儿出生体重较高(P=0·047),但与密切随访组相比,对巨大儿没有影响。作为生活方式干预的一部分,由临床营养师进行个体化咨询可改善 GDM 高危孕妇的膳食脂肪摄入质量。