University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK.
Int J Clin Pract. 2011 Dec;65(12):1274-82. doi: 10.1111/j.1742-1241.2011.02796.x.
Heart failure (HF) is a common condition leading to an unfavourable prognosis and impaired quality of life. In this review, we provide an overview of published literature on possible epidemiological and pathophysiological differences between patients with systolic HF of South Asian origin and those from other ethnic groups (mainly White). Systolic HF tends to manifest earlier among South Asians and with frequent hospital admissions. However, survival for such patients appears to be significantly better compared with the White group, which might be associated with different patterns of HF. For example, this could be attributed to a lower prevalence of left ventricular systolic dysfunction in South Asian subjects. Indeed, the high prevalence of hypertension and diabetes among South Asians may predispose to diastolic HF with preserved systolic function. In addition, because of underrepresentation of South Asians in clinical trials, there are little data on optimal management of this ethnic group.
心力衰竭（HF）是一种常见病症，可导致预后不良和生活质量受损。在本次综述中，我们概述了已发表的有关南亚裔和其他族裔（主要是白人）患者之间可能存在的流行病学和病理生理学差异的文献。南亚裔人群的收缩性心力衰竭发病较早，且经常住院治疗。然而，与白人相比，这些患者的生存率似乎明显更高，这可能与心力衰竭的不同模式有关。例如，这可能归因于南亚裔人群中心室收缩功能障碍的发生率较低。事实上，南亚裔人群中高血压和糖尿病的高发可能导致舒张性心力衰竭伴收缩功能保留。此外，由于南亚裔人群在临床试验中的代表性不足，关于该人群的最佳管理的数据很少。
