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剖宫产足月新生儿脐带血采集:一项随机对照试验。

Umbilical cord milking in term infants delivered by cesarean section: a randomized controlled trial.

机构信息

University of Rhode Island, College of Nursing, Kingston, RI, USA.

出版信息

J Perinatol. 2012 Aug;32(8):580-4. doi: 10.1038/jp.2011.159. Epub 2011 Nov 17.

DOI:10.1038/jp.2011.159
PMID:22094494
Abstract

OBJECTIVE

The study's objective was to compare hematocrit (Hct) levels at 36 to 48 h of age in term infants delivered by cesarean section exposed to immediate cord clamping or umbilical cord milking (UCM).

STUDY DESIGN

In this randomized controlled trial, 24 women scheduled for elective cesarean section were randomized to either immediate clamping (<10 s) or UCM (milked × 5 by the obstetrical provider) at birth.

RESULT

All subjects received their allocated intervention. The milking group had a smaller placental residual blood volume (13.2±5.6 vs 19.2±5.4 ml kg(-1), P=0.01) and higher Hct levels at 36 to 48 h (57.5±6.6 vs 50.0±6.4 %, P=0.01). Five infants (42%) in the immediate group had a Hct of ≤47%, indicative of anemia.

CONCLUSION

UCM results in placental transfusion in term infants at the time of elective cesarean section with higher Hct levels at 36 to 48 h of age.

摘要

目的

本研究旨在比较行择期剖宫产术的足月婴儿在出生后 36 至 48 小时的血细胞比容(Hct)水平,这些婴儿在出生时接受即刻脐带夹闭或脐带挤奶(UCM)处理。

研究设计

在这项随机对照试验中,24 名计划行择期剖宫产术的妇女被随机分为即刻夹闭组(<10 秒)或 UCM 组(由产科医生挤奶×5 次)。

结果

所有受试者均接受了其分配的干预措施。挤奶组的胎盘残留血量较少(13.2±5.6 比 19.2±5.4 ml·kg(-1),P=0.01),出生后 36 至 48 小时的 Hct 水平较高(57.5±6.6 比 50.0±6.4%,P=0.01)。即刻夹闭组有 5 名婴儿(42%)的 Hct 低于 47%,表明存在贫血。

结论

UCM 可在择期行剖宫产术的足月婴儿中进行胎盘输血,使出生后 36 至 48 小时的 Hct 水平升高。

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