Sharp Mary Birch Hospital for Women and Newborns, Sharp Neonatal Research Institute, San Diego, CA, USA.
Thomas Jefferson University/Nemours, Philadelphia, PA, USA.
Semin Perinatol. 2023 Jun;47(4):151742. doi: 10.1016/j.semperi.2023.151742. Epub 2023 Mar 17.
Cord management in non-vigorous newborns remains up for debate, as limited studies have validated strategies in this high-risk population. While multiple national and international governing bodies now recommend the routine practice of delayed cord clamping (DCC) in vigorous neonates, these organizations have not reached a consensus on the appropriate approach in non-vigorous neonates. Benefits of placental transfusion are greatly needed amongst non-vigorous neonates who are at risk of asphyxiation-associated mortality and morbidities, but the need for immediate resuscitation complicates matters. This chapter discusses the physiological benefits of placental transfusion for non-vigorous neonates and reviews the available literature on different umbilical cord management strategies for this population.
在非活力新生儿中,脐带管理仍存在争议,因为有限的研究已经验证了在这个高风险人群中的策略。虽然现在多个国家和国际管理机构都建议在活力新生儿中常规实施延迟脐带夹闭(DCC),但这些组织在非活力新生儿中尚未就适当的方法达成共识。在有窒息相关死亡率和发病率风险的非活力新生儿中,非常需要胎盘输血的益处,但立即复苏的需要使情况变得复杂。本章讨论了胎盘输血对非活力新生儿的生理益处,并回顾了针对该人群的不同脐带管理策略的现有文献。