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Glittre日常生活活动能力测试能否区分慢性阻塞性肺疾病患者与健康受试者的功能能力?

Can the Glittre ADL test differentiate the functional capacity of COPD patients from that of healthy subjects?

作者信息

Corrêa Krislainy S, Karloh Manuela, Martins Letícia Q, dos Santos Karoliny, Mayer Anamaria F

机构信息

Universidade Federal de Goiás, Goiânia, GO, Brazil.

出版信息

Rev Bras Fisioter. 2011 Nov-Dec;15(6):467-73. doi: 10.1590/s1413-35552011005000034. Epub 2011 Nov 21.

DOI:10.1590/s1413-35552011005000034
PMID:22094546
Abstract

BACKGROUND

The Glittre ADL (TGlittre) test is a specifically designed to assess functional limitation in chronic obstructive pulmonary disease (COPD) patients. However, it is not known if it can differentiate the performance of these patients from healthy subjects.

OBJECTIVES

To investigate whether the Glittre ADL test is able to differentiate the functional capacity of COPD patients from that of healthy subjects and to compare the cardiorespiratory response between Glittre ADL and the six-minute walk test (6MWT).

METHODS

The study included 10 patients with COPD (GOLD 2 to 4) and 10 healthy subjects matched by age who performed the following: spirometry pre- and post-bronchodilator, a Glittre ADL test and two 6MWT on two consecutive days.

RESULTS

The performance of COPD (FEV1%pred= 38.1±11.8, age=64±10 years, BMI=23.7±5.2 kg/ m²) was worse than the control group on TGlittre (5.26±2.9 min, 3.3±0.3 min, p<0.05) and 6MWT (434.97±105.18 m vs. 593.25±87.36 m, p<0.05). TGlittre correlated with the physical activity domain of the London Chest Activity of Daily Living (LCADL) scale (r=0.67, p<0.05) and with 6MWT when the total sample was analyzed (r=-0.64, p<0.05). The COPD group had a statistically higher (p<0.05) increase in dyspnea (Borg scale) than the control group for both TGlittre and 6MWT, with a similar heart rate and peripheral oxygen saturation variation in both groups (p>0.05).

CONCLUSIONS

The performance of COPD patients is worse than that of healthy subjects on the Glittre ADL test, with a greater increase in dyspnea and similar heart rates.

摘要

背景

Glittre日常活动能力(TGlittre)测试是专门为评估慢性阻塞性肺疾病(COPD)患者的功能受限而设计的。然而,尚不清楚它是否能区分这些患者与健康受试者的表现。

目的

研究Glittre日常活动能力测试是否能够区分COPD患者与健康受试者的功能能力,并比较Glittre日常活动能力测试与六分钟步行试验(6MWT)之间的心肺反应。

方法

该研究纳入了10例COPD患者(GOLD 2至4级)和10名年龄匹配的健康受试者,他们进行了以下检查:支气管扩张剂前后的肺活量测定、一次Glittre日常活动能力测试以及连续两天的两次6MWT。

结果

COPD患者(预计第一秒用力呼气容积百分比[FEV1%pred]=38.1±11.8,年龄=64±10岁,体重指数[BMI]=23.7±5.2kg/m²)在TGlittre测试(5.26±2.9分钟,3.3±0.3分钟,p<0.05)和6MWT(434.97±105.18米对593.25±87.36米,p<0.05)中的表现均比对照组差。当分析整个样本时,TGlittre与伦敦胸部日常生活活动(LCADL)量表的身体活动领域相关(r=0.67,p<0.05),并与6MWT相关(r=-0.64,p<0.05)。对于TGlittre和6MWT,COPD组的呼吸困难(Borg量表)增加在统计学上高于对照组(p<0.05),两组的心率和外周血氧饱和度变化相似(p>0.05)。

结论

在Glittre日常活动能力测试中,COPD患者的表现比健康受试者差,呼吸困难增加更明显,心率相似。

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