Font-Vizcarra Lluís, Lozano Luis, Ríos José, Forga Maria Teresa, Soriano Alex
Department of Orthopedics and Trauma Surgery, Parc Sanitari Sant Joan de Dèu, Sant Boi de Llobregat, Barcelona, Spain.
Int J Artif Organs. 2011 Sep;34(9):876-81. doi: 10.5301/ijao.5000025.
To assess the potential relationship between preoperative nutritional status, including anthropometric parameters, and infection following total knee replacement surgery.
A total of 213 patients undergoing total knee replacement between December 2007 and May 2008 were prospectively studied. Patients with rheumatoid arthritis were excluded. For each patient we pre-operatively checked biochemical and anthropometric parameters of nutrition information about co-morbidities such as diabetes and high blood pressure, ASA score, age, and gender. Information about early infections, both superficial and deep, was collected. A descriptive statistical analysis and univariate/multivariate logistic regression model for risk factors were performed.
Eleven patients (5.16%) had an infection, 5 deep and 6 superficial. Neither co-morbidities nor preoperatively biochemical parameters were associated with infection. However, in the univariate logistic regression model there was an inversely proportional relationship between triceps skinfold (TSF) and infection. After adjusting for age, ASA score and gender (multivariate logistic regression), TSF remained significantly associated with infection.
There was a statistically significant association between TSF and post-operative infection risk after TKR.
Level I (Prospective prognostic study).
评估术前营养状况（包括人体测量参数）与全膝关节置换术后感染之间的潜在关系。
对2007年12月至2008年5月期间接受全膝关节置换的213例患者进行前瞻性研究。排除类风湿性关节炎患者。对于每位患者，我们术前检查了营养状况的生化和人体测量参数、合并症（如糖尿病和高血压）信息、美国麻醉医师协会（ASA）评分、年龄和性别。收集了有关浅表和深部早期感染的信息。进行了描述性统计分析以及危险因素的单变量/多变量逻辑回归模型分析。
11例患者（5.16%）发生感染，5例深部感染，6例浅表感染。合并症和术前生化参数均与感染无关。然而，在单变量逻辑回归模型中，肱三头肌皮褶厚度（TSF）与感染呈反比关系。在对年龄、ASA评分和性别进行校正后（多变量逻辑回归），TSF仍与感染显著相关。
全膝关节置换术后，TSF与术后感染风险之间存在统计学上的显著关联。
I级（前瞻性预后研究）。
