Soloff Michelle A, Vargas Maria V, Wei Chapman, Ohnona Ashley, Tyan Paul, Gu Alex, Georgakopoulos Bianca, Thomas Caroline A, Quan Theodore, Barishansky Seth, Moawad Gaby
Department of Obstetrics and Gynecology, North Shore University Hospital and Long Island Jewish Medical Center, Manhasset, NY.
Department of Obstetrics and Gynecology, George Washington University School of Medicine and Health Sciences, Washington, DC.
JSLS. 2021 Jan-Mar;25(1). doi: 10.4293/JSLS.2020.00084.
Malnutrition continues to be pervasive among the general population, with rates as high as 50% of patients undergoing surgical procedures. Data is limited about women undergoing surgery for non-malignant gynecologic indications (generally elective laparoscopic hysterectomies, after failed conservative measures). With the significant increase in benign gynecologic surgery, it is of the upmost importance that surgeons optimize modifiable risk factors for patients undergoing laparoscopic hysterectomy. The purpose of this study is to identify the impact of malnutrition on postoperative outcomes in patients undergoing laparoscopic hysterectomy for benign conditions.
A retrospective cohort study was conducted utilizing data that was collected through the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) Database. All patients that underwent laparoscopic hysterectomy for benign indications were identified. Patients with malnutrition were identified by either low albumin (≤ 3.5 g/dL), low body mass index (≤ 18.5), or 10% weight loss within 6 months. The frequency of postoperative complications was evaluated with univariate and multivariate analyses where appropriate.
Following adjustment, multivariate analysis illustrated pre-operative malnutrition to be a risk factor for the following complications: any complication, death, bleeding requiring transfusion, wound, cardiac, pulmonary, renal, thromboembolic, sepsis complications, extended length of stay, and reoperation (p ≤ 0.05 for all).
Malnourished patients were at significantly higher risk of developing postoperative complications during the acute postoperative period. With elective laparoscopic hysterectomies, pre-operative evaluation and intervention for malnutrition should be considered to improve nutritional status.
营养不良在普通人群中仍然普遍存在,接受外科手术的患者中这一比例高达50%。关于因非恶性妇科指征接受手术的女性(通常是在保守治疗失败后进行选择性腹腔镜子宫切除术)的数据有限。随着良性妇科手术的显著增加,外科医生优化腹腔镜子宫切除术患者的可改变风险因素至关重要。本研究的目的是确定营养不良对因良性疾病接受腹腔镜子宫切除术患者术后结局的影响。
利用通过美国外科医师学会国家外科质量改进计划(NSQIP)数据库收集的数据进行了一项回顾性队列研究。确定了所有因良性指征接受腹腔镜子宫切除术的患者。营养不良患者通过低白蛋白(≤3.5 g/dL)、低体重指数(≤18.5)或6个月内体重减轻10%来确定。在适当情况下,通过单因素和多因素分析评估术后并发症的发生率。
调整后,多因素分析表明术前营养不良是以下并发症的危险因素:任何并发症、死亡、需要输血的出血、伤口、心脏、肺部、肾脏、血栓栓塞、败血症并发症、住院时间延长和再次手术(所有p≤0.05)。
营养不良患者在术后急性期发生术后并发症的风险显著更高。对于选择性腹腔镜子宫切除术,应考虑对营养不良进行术前评估和干预,以改善营养状况。