可乐定能否治愈安非他明依赖？
[Cure of amineptine dependence with clonidine?].
作者信息
Bourin M, Gest D, Baudot S
机构信息
Pharmacologie Clinique et Pharmacovigilance, C.H.R. de Nantes.
出版信息
Encephale. 1990 Jul-Aug;16(4):261-3.
PMID:2209478
Abstract
Two patients with dependence to amineptine were treated with clonidine which is used in morphine withdrawals. After some days, the two patients stopped amineptine intake. The only way of action seems to be the potentialization of amineptine by clonidine, as probed in mice, or the increase of sensibilization of alpha 2 adrenoreceptors.
摘要
两名对安咪奈丁有依赖性的患者接受了可乐定治疗，可乐定用于吗啡戒断治疗。几天后，这两名患者停止了安咪奈丁的摄入。唯一的作用方式似乎是可乐定对安咪奈丁的增效作用（如在小鼠身上所探究的），或者是α2肾上腺素能受体敏感性的增加。
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