Instituto Estadual de Diabetes e Endocrinologia do Rio de Janeiro (IEDE), Rio de Janeiro, Brasil.
Obesity (Silver Spring). 2012 Feb;20(2):440-3. doi: 10.1038/oby.2011.343. Epub 2011 Nov 17.
BMI is a widely used method to evaluate adiposity. However, it has several limitations, particularly an inability to differentiate lean from fat mass. A new method, body adiposity index (BAI), has been recently proposed as a new measurement capable to determine fat excess better than BMI. The aim of this study was to investigate BAI as a mean to evaluate adiposity in a group of women with familial partial lipodystrophy (FPLD) and compare it with BMI. Thirteen women with FLPD Dunnigan type (FPLD2) and 13 healthy volunteers matched by age and BMI were studied. Body fat content and distribution were analyzed by dual X-ray absorptiometry (DXA). Plasma leptin was also measured. BAI was significantly lower in FPLD2 in comparison to control group (24.6 ± 1.5 vs. 30.4 ± 4.3; P < 0.001) and presented a more significant correlation with total fat (%) (r = 0.71; P < 0.001) and fat Mass (g) (r = 0.80; P < 0.001) than BMI (r = 0.27; P = 0.17 for total fat and r = 0.52; P = 0.006 for fat mass). There was a correlation between leptin and BAI (r = 0.57; P = 0.01), [corrected] but not between leptin and BMI. In conclusion, BAI was able to catch differences in adiposity in a sample of FPLD2 patients. It also correlated better with leptin levels than BMI. Therefore, we provide further evidence that BAI may become a more reliable indicator of fat mass content than the currently available measurements.
体重指数（BMI）是评估肥胖的常用方法。然而，它存在一些局限性，特别是无法区分瘦体重和脂肪量。最近提出了一种新的方法，即身体脂肪指数（BAI），作为一种能够更好地确定脂肪过多的新测量方法。本研究旨在研究 BAI 作为评估一组家族性部分脂肪营养不良（FPLD）女性肥胖的一种方法，并将其与 BMI 进行比较。研究了 13 名 Dunnigan 型家族性部分脂肪营养不良（FPLD2）女性和 13 名年龄和 BMI 匹配的健康志愿者。通过双能 X 线吸收法（DXA）分析体脂肪含量和分布。还测量了血浆瘦素。与对照组相比，FPLD2 中的 BAI 显著降低（24.6 ± 1.5 与 30.4 ± 4.3；P < 0.001），并且与总脂肪（%）（r = 0.71；P < 0.001）和脂肪质量（g）（r = 0.80；P < 0.001）的相关性比 BMI（r = 0.27；P = 0.17 用于总脂肪，r = 0.52；P = 0.006 用于脂肪质量）更显著。瘦素与 BAI 之间存在相关性（r = 0.57；P = 0.01），[校正]但与 BMI 之间没有相关性。总之，BAI 能够捕捉到 FPLD2 患者样本中肥胖的差异。它与瘦素水平的相关性也优于 BMI。因此，我们提供了进一步的证据表明，BAI 可能成为比目前可用的测量方法更可靠的脂肪质量含量指标。
