EMBL-EBI, the European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
Nucleic Acids Res. 2012 Jan;40(Database issue):D64-70. doi: 10.1093/nar/gkr937. Epub 2011 Nov 16.
The BioSample Database (http://www.ebi.ac.uk/biosamples) is a new database at EBI that stores information about biological samples used in molecular experiments, such as sequencing, gene expression or proteomics. The goals of the BioSample Database include: (i) recording and linking of sample information consistently within EBI databases such as ENA, ArrayExpress and PRIDE; (ii) minimizing data entry efforts for EBI database submitters by enabling submitting sample descriptions once and referencing them later in data submissions to assay databases and (iii) supporting cross database queries by sample characteristics. Each sample in the database is assigned an accession number. The database includes a growing set of reference samples, such as cell lines, which are repeatedly used in experiments and can be easily referenced from any database by their accession numbers. Accession numbers for the reference samples will be exchanged with a similar database at NCBI. The samples in the database can be queried by their attributes, such as sample types, disease names or sample providers. A simple tab-delimited format facilitates submissions of sample information to the database, initially via email to biosamples@ebi.ac.uk.
生物样本数据库（http://www.ebi.ac.uk/biosamples）是 EBI 中的一个新数据库，用于存储分子实验中使用的生物样本的信息，如测序、基因表达或蛋白质组学。生物样本数据库的目标包括：（i）在 EBI 数据库（如 ENA、ArrayExpress 和 PRIDE）中一致地记录和链接样本信息；（ii）通过允许在向分析数据库提交数据时一次性提交样本描述并在以后引用它们，为 EBI 数据库提交者减少数据输入工作；（iii）通过样本特征支持跨数据库查询。数据库中的每个样本都分配有一个访问号。该数据库包括越来越多的参考样本，如细胞系，这些样本在实验中被反复使用，并且可以通过其访问号从任何数据库中轻松引用。参考样本的访问号将与 NCBI 的类似数据库交换。可以根据样本的属性（如样本类型、疾病名称或样本提供者）查询数据库中的样本。一个简单的制表符分隔格式便于将样本信息提交到数据库，最初通过电子邮件发送到 biosamples@ebi.ac.uk。
