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ArrayExpress 更新——数据库增长趋势及与数据分析工具的链接。

ArrayExpress update--trends in database growth and links to data analysis tools.

机构信息

Functional Genomics Team, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK.

出版信息

Nucleic Acids Res. 2013 Jan;41(Database issue):D987-90. doi: 10.1093/nar/gks1174. Epub 2012 Nov 27.


DOI:10.1093/nar/gks1174
PMID:23193272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3531147/
Abstract

The ArrayExpress Archive of Functional Genomics Data (http://www.ebi.ac.uk/arrayexpress) is one of three international functional genomics public data repositories, alongside the Gene Expression Omnibus at NCBI and the DDBJ Omics Archive, supporting peer-reviewed publications. It accepts data generated by sequencing or array-based technologies and currently contains data from almost a million assays, from over 30 000 experiments. The proportion of sequencing-based submissions has grown significantly over the last 2 years and has reached, in 2012, 15% of all new data. All data are available from ArrayExpress in MAGE-TAB format, which allows robust linking to data analysis and visualization tools, including Bioconductor and GenomeSpace. Additionally, R objects, for microarray data, and binary alignment format files, for sequencing data, have been generated for a significant proportion of ArrayExpress data.

摘要

ArrayExpress 功能基因组学数据档案(http://www.ebi.ac.uk/arrayexpress)是三个国际性功能基因组学公共数据存储库之一,其他两个分别是 NCBI 的基因表达综合数据库和 DDBJ 组学档案,均支持经过同行评审的出版物。它接受基于测序或基于阵列的技术生成的数据,目前包含近 100 万个检测,来自超过 30000 个实验。基于测序的提交比例在过去 2 年中显著增长,并且在 2012 年达到了所有新数据的 15%。所有数据都可以从 ArrayExpress 以 MAGE-TAB 格式获取,这允许与数据分析和可视化工具(包括 Bioconductor 和 GenomeSpace)进行稳健链接。此外,为了显著一部分的 ArrayExpress 数据,已经为微阵列数据生成了 R 对象,以及为测序数据生成了二进制对齐格式文件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf89/3531147/602ff18356b0/gks1174f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf89/3531147/602ff18356b0/gks1174f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf89/3531147/602ff18356b0/gks1174f1p.jpg

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本文引用的文献

[1]
The DNA Data Bank of Japan launches a new resource, the DDBJ Omics Archive of functional genomics experiments.

Nucleic Acids Res. 2011-11-22

[2]
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Nucleic Acids Res. 2011-11-16

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Nucleic Acids Res. 2011-1

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Genome Biol. 2010-8-25

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[10]
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Bioinformatics. 2010-3-3

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