Rakar S, Kovacic J
University Department of Obstetrics and Gynecology, Ljubljana, Yugoslavia.
Eur J Gynaecol Oncol. 1990;11(3):233-5.
The 5 year survival rates of 228 patients with endometrial cancer treated in the period 1978-1982 according to the prognostic factors (stage, grade, depth of myometrial invasion, lymph node metastasis) is presented. All patients were treated with primary surgery consisting of classical Wertheim operation with lymphadenectomy (98 cases-43%), total abdominal hysterectomy with bilateral salpingo-oophorectomy with lymphadenectomy (52 cases-48%) and without lymphadenectomy (55 cases-52%) and vaginal hysterectomy with bilateral salpingo-oophorectomy (23 cases-10%). All patients except 6.6% were postoperatively irradiated. The 5 year survival for all stages was 74.6%. In SI cases it was 83.8%, in SII 57.9% and only 37.5% in SIII group. The survival was 90.1% in patients with superficial myometrial invasion and 56.4% in cases of deeper invasion. The survival of patients with node metastasis (8.6%) was only 39.5%, irrespective of the type of surgery and postoperative external irradiation. Vaginal recurrences were observed in 3.9%, and all the patients died. To improve the results it is necessary to individualize the treatment according to the pathologic and clinical prognostic factors.
本文呈现了1978年至1982年间接受治疗的228例子宫内膜癌患者根据预后因素（分期、分级、肌层浸润深度、淋巴结转移）的5年生存率。所有患者均接受了初次手术，包括经典的Wertheim手术加淋巴结清扫术（98例，占43%）、全腹子宫切除术加双侧输卵管卵巢切除术加淋巴结清扫术（52例，占48%）以及不加淋巴结清扫术（55例，占52%）和经阴道子宫切除术加双侧输卵管卵巢切除术（23例，占10%）。除6.6%的患者外，所有患者术后均接受了放疗。所有分期的5年生存率为74.6%。I期患者为83.8%，II期为57.9%，III期组仅为37.5%。肌层浅浸润患者的生存率为90.1%，深浸润患者为56.4%。有淋巴结转移患者（8.6%）的生存率仅为39.5%，与手术类型和术后体外放疗无关。观察到3.9%的患者出现阴道复发，所有这些患者均死亡。为改善治疗效果，有必要根据病理和临床预后因素进行个体化治疗。
