Fantasia M, Ricci N, Manuppella A, Martini A, Filetici E, Laurelli T
Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanità, Rome, Italy.
Epidemiol Infect. 1990 Oct;105(2):317-23. doi: 10.1017/s0950268800047919.
Thirty-eight Salmonella typhimurium strains isolated from December 1987 to March 1988 in Isernia, Central Italy, were characterized on the basis of their phage type, resistance to antimicrobials and plasmid profiles. According to their phage types, the isolates could be assigned to one of six groups, the prevalent one being PT 195 which accounted for 73.6% of isolates. On the basis of their plasmid content, the isolates could be assigned to one of ten groups. The prevalent plasmid profile (60.0; 6.0; 4.3; 4.0; 3.2 megadaltons) was found in 60.4% of isolates. All the isolates from a particular food (salsicce), and as most of isolates from humans who had consumed this food belonged to phage type 195 and were of the same plasmid profile. The combined use of phage typing and DNA plasmid analysis proved to be a useful tool in identifying epidemiologically related isolates in this investigation.
1987年12月至1988年3月间从意大利中部伊塞尔尼亚分离出的38株鼠伤寒沙门氏菌，根据其噬菌体类型、对抗菌药物的耐药性和质粒图谱进行了特征分析。根据噬菌体类型，这些分离株可分为六组之一，其中最常见的是PT 195，占分离株的73.6%。根据质粒含量，这些分离株可分为十组之一。在60.4%的分离株中发现了最常见的质粒图谱（60.0；6.0；4.3；4.0；3.2兆道尔顿）。来自特定食物（意大利香肠）的所有分离株，以及食用该食物的大多数人类分离株都属于噬菌体类型195，且具有相同的质粒图谱。在本次调查中，噬菌体分型和DNA质粒分析的联合使用被证明是识别流行病学相关分离株的有用工具。
