Lu Huifeng, Ding Shuang, Zheng Ping
Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China.
Wei Sheng Wu Xue Bao. 2011 Aug;51(8):1014-22.
Anaerobic ammonium oxidation (anammox) is a biological process by which ammonium is oxidized to dinitrogen gas by using nitrite as the electrons acceptor. Anaerobic ammonium-oxidizing bacteria play an important role in nitrogen removal from wastewater and global N-cycle. The study of metabolism of anammox bacteria will help us understand the anammox mechanism and develop anammox biotechnology. Anammox bacteria are chemoautotrophic bacteria that use CO, or HCO3- as carbon source and obtain their energy from the conversion of ammonium and nitrite into dinitrogen gas. Hydrazine has been detected as an intermediate in the anammox pathway, while hydroxylamine and nitric oxide have not been detected yet. The genomic data indicate that anammox bacteria fix carbon dioxide through acetyl-CoA pathway. The proposed anammox pathway is consistent with the available experimental data, thermodynamical calculation and biochemical determination and as well as the Ockham's razor principal.
厌氧氨氧化是一种生物过程，通过该过程，铵利用亚硝酸盐作为电子受体被氧化为氮气。厌氧氨氧化细菌在废水脱氮和全球氮循环中发挥着重要作用。对厌氧氨氧化细菌代谢的研究将有助于我们理解厌氧氨氧化机制并开发厌氧氨氧化生物技术。厌氧氨氧化细菌是化学自养细菌，它们利用CO₂ 或HCO₃⁻ 作为碳源，并通过将铵和亚硝酸盐转化为氮气来获取能量。肼已被检测为厌氧氨氧化途径中的一种中间产物，而羟胺和一氧化氮尚未被检测到。基因组数据表明，厌氧氨氧化细菌通过乙酰辅酶A途径固定二氧化碳。所提出的厌氧氨氧化途径与现有的实验数据、热力学计算和生化测定以及奥卡姆剃刀原则相一致。
