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近红外荧光淋巴管腹腔镜结肠和横结肠检查。

Near infrared fluorescence lymphatic laparoscopy of the colon and mesocolon.

机构信息

Department of Surgery, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Colorectal Dis. 2011 Nov;13 Suppl 7:70-3. doi: 10.1111/j.1463-1318.2011.02787.x.

Abstract

During surgery, a surgeon relies on the vision of his eyes and the touch of his hands. While laparoscopic surgery for colon cancer has proven to be safe and effective, it still remains a technically difficult procedure. Although it is associated with reduced haptic feedback, by enforcing the power of visual guidance, the loss of this feedback can be (partly) compensated for. Here we describe how the use of near-infrared dyes and fluorescence laparoscopy could help improve tumour staging and therefore lead to better selection of patients for postoperative adjuvant chemotherapy. More controversially, and analogous to melanoma and breast cancer surgery with sentinel node biopsy, we speculate that local resection with SLN harvesting in early colon cancer might change the therapeutic and surgical strategy in colon cancer.

摘要

在手术过程中,外科医生依赖于眼睛的视觉和双手的触感。虽然腹腔镜结肠癌手术已被证明是安全有效的,但它仍然是一种技术上具有挑战性的手术。尽管它与触觉反馈减少有关,但通过增强视觉引导的力量,这种反馈的损失可以(部分)得到补偿。在这里,我们描述了近红外染料和荧光腹腔镜检查的使用如何有助于提高肿瘤分期,从而更好地选择接受术后辅助化疗的患者。更具争议性的是,类似于黑色素瘤和乳腺癌的前哨淋巴结活检手术,我们推测早期结肠癌的局部切除术和 SLN 采集可能会改变结肠癌的治疗和手术策略。

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