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荧光引导腹部手术中吲哚菁绿和亚甲蓝使用实用指南

A practical guide for the use of indocyanine green and methylene blue in fluorescence-guided abdominal surgery.

作者信息

van Manen Labrinus, Handgraaf Henricus J M, Diana Michele, Dijkstra Jouke, Ishizawa Takeaki, Vahrmeijer Alexander L, Mieog Jan Sven David

机构信息

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

IHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.

出版信息

J Surg Oncol. 2018 Aug;118(2):283-300. doi: 10.1002/jso.25105. Epub 2018 Jun 24.

DOI:10.1002/jso.25105
PMID:29938401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6175214/
Abstract

Near-infrared (NIR) fluorescence imaging is gaining clinical acceptance over the last years and has been used for detection of lymph nodes, several tumor types, vital structures and tissue perfusion. This review focuses on NIR fluorescence imaging with indocyanine green and methylene blue for different clinical applications in abdominal surgery with an emphasis on oncology, based on a systematic literature search. Furthermore, practical information on doses, injection times, and intraoperative use are provided.

摘要

近红外（NIR）荧光成像在过去几年中逐渐获得临床认可，并已用于检测淋巴结、多种肿瘤类型、重要结构和组织灌注。基于系统的文献检索，本综述重点关注吲哚菁绿和亚甲蓝在腹部手术不同临床应用中的近红外荧光成像，重点是肿瘤学。此外，还提供了关于剂量、注射时间和术中使用的实用信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/3ee18512f79c/JSO-118-283-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/74d3a18281bd/JSO-118-283-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/21fe50a9faea/JSO-118-283-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/4ef694534a5e/JSO-118-283-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/59d5228df14d/JSO-118-283-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/3ee18512f79c/JSO-118-283-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/74d3a18281bd/JSO-118-283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/2bee1fc3a7b7/JSO-118-283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/21fe50a9faea/JSO-118-283-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/59d5228df14d/JSO-118-283-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdb/6175214/3ee18512f79c/JSO-118-283-g006.jpg

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Int J Surg. 2017 Nov;47:13-17. doi: 10.1016/j.ijsu.2017.09.015. Epub 2017 Sep 14.
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A pilot study to assess near infrared laparoscopy with indocyanine green (ICG) for intraoperative sentinel lymph node mapping in early colon cancer.
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Nanomaterials (Basel). 2025 May 28;15(11):811. doi: 10.3390/nano15110811.
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Molecular-Targeted Fluorescence Lymph Node Imaging Could Play a Clinical Role in the Surgical Setting: A Systematic Review.分子靶向荧光淋巴结成像在手术场景中可能发挥临床作用：一项系统评价。
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