Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Virus Res. 2012 Mar;164(1-2):43-5. doi: 10.1016/j.virusres.2011.11.003. Epub 2011 Nov 11.
Porcine circovirus 2 (PCV2) may induce reproductive failure (return to oestrus, embryonic death, mummification, weak- and stillborn piglets) and postweaning multisystemic wasting syndrome (PMWS). Furthermore, it may modulate the immunity in such a way that it aggravates the outcome of many bacterial and viral infections. In the present paper, the cellular tropism and entry of PCV2 are described and linked with the pathological and clinical consequences.
猪圆环病毒 2 型(PCV2)可能引起繁殖失败(返情、胚胎死亡、木乃伊化、弱仔和死胎)和断奶后多系统衰竭综合征(PMWS)。此外,它可能通过调节免疫作用,加重许多细菌和病毒感染的结果。本文描述了 PCV2 的细胞嗜性和进入,并将其与病理和临床后果联系起来。